VIMP

Gene Symbol	VIMP
Entrez Gene	55829
Alt Symbol	AD-015, ADO15, SBBI8, SELS, SEPS1
Species	Human
Gene Type	protein-coding
Description	VCP-interacting membrane protein
Other Description	selenoprotein S
Swissprots	Q3B771 Q9P0I6 Q9BQE4
Accessions	EAX02295 Q9BQE4 AA487772 AF157317 AAF67483 AF328864 AAK15708 AI673590 AK026455 AK097011 AK225955 AK314723 AY324824 AAP85541 AY618665 AAT46592 BC005840 AAH05840 BC107774 AAI07775 BG829960 BI494034 BQ014190 BU740863 DQ578816 DW430970 NM_018445 NP_060915 NM_203472 NP_982298
Function	Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination. {ECO:0000269|PubMed:15215856}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm {ECO:0000250}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SELS full length protein - ab163245 from Abcam Category Protein Source Wheat germ Species Human

SELS Antibody Blocking Peptide - LS-E17397 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SELS Recombinant Protein - H00055829-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SelS Protein - GTX109311-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

SELS Blocking Peptide - 33R-7030 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Selenoprotein S (SELS) - H00055829-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Selenoprotein S (SELS) - H00055829-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SELS fusion protein - Ag7928 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

SELS fusion protein - ag7816 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human SELS, GST-tagged - SELS-2573H from Creative Biomart Category Protein Source E.coli Species Human

SELS Protein - NBP1-89558PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SELS-Antibody-Center-Blocking-Peptide - BP9171c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

VIMP Peptide, Human - M34GP17279H from Creative Peptides Category Peptide Source Synthetic. Species Human

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