VIMP

Gene Symbol VIMP
Entrez Gene 55829
Alt Symbol AD-015, ADO15, SBBI8, SELS, SEPS1
Species Human
Gene Type protein-coding
Description VCP-interacting membrane protein
Other Description selenoprotein S
Swissprots Q3B771 Q9P0I6 Q9BQE4
Accessions EAX02295 Q9BQE4 AA487772 AF157317 AAF67483 AF328864 AAK15708 AI673590 AK026455 AK097011 AK225955 AK314723 AY324824 AAP85541 AY618665 AAT46592 BC005840 AAH05840 BC107774 AAI07775 BG829960 BI494034 BQ014190 BU740863 DQ578816 DW430970 NM_018445 NP_060915 NM_203472 NP_982298
Function Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination. {ECO:0000269|PubMed:15215856}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm {ECO:0000250}.
Top Pathways Protein processing in endoplasmic reticulum

VIMP Antibody - 13738 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using VIMP Antibody.

Selenoprotein S (D-1) - sc-365498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
elenoprotein S (D-1): sc-365498. Western blot analysis of Selenoprotein S expression in non-transfected: sc-117752 (A) and mouse Selenoprotein S transfected: sc-127522 (B) 293T whole cell lysates.

Selenoprotein S (H-189) - sc-98774 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Selenoprotein S (FL-189): sc-98774. Western blot analysis of Selenoprotein S expression in non-transfected: sc-117752 (A) and mouse Selenoprotein S transfected: sc-127522 (B) 293T whole cell lysates.

Selenoprotein S (N-13) - sc-104653 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Selenoprotein S (N-13): sc-104653. Western blot analysis of Selenoprotein S expression in IMR-32 whole cell lysate.

Anti-SELS antibody - ab198263 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling SELS with ab198263 at 1/20 dilution.

Anti-SELS antibody - ab190247 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SELS antibody (ab190247) at 0.4 µg/mlLane 1 : HeLa whole cell lysate in NETN bufferLane 2 : HeLa whole cell lysate in RIPA bufferLane 3 : 293T whole cell lysate in NETN bufferLane 4 : Jurkat whole cell lysate in RIPA bufferLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-SELS antibody - ab84577 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SELS antibody (ab84577) at 1 µg/ml + Human fetal muscle lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SELS antibody - ab89760 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-SELS antibody (ab89760) at 1 µg/ml + A431 cell lysate at 50 µgdeveloped using the ECL technique

Anti-SELS antibody - Aminoterminal end - ab58656 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SELS Antibody (aa125-175) - LS-C291003 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Selenoprotein S by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN buffer from HeLa cells. Antibodies: Affinity purified rabbit anti-Selenoprotein S antibody used for IP at 6 ug per reaction. Selenoprotein S was also immunoprecipitated by rabbit anti-Selenoprotein S antibody BL16285. For blotting immunoprecipitated Selenoprotein S, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-SELS Antibody (aa72-121) IHC-plus™ - LS-B5808 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SELS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5808 concentration 5 ug/ml.

Anti-SELS Antibody (aa44-74) - LS-C168947 from LifeSpan Bioscience

Prices $250.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of SELS Antibody (Center) in 293 cell line lysates (35 ug/lane). SELS (arrow) was detected using the purified Pab.

SELS Antibody - NBP1-89558 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SELS Antibody [NBP1-89558] - Staining of human cell line U-251MG shows positivity in endoplasmic reticulum.

SELS Antibody - NBP1-59042 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SELS Antibody [NBP1-59042] - Human Fetal Muscle lysate, concentration 0.2-1 ug/ml.

SELS Antibody - NBP2-32096 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SELS Antibody [NBP2-32096] - Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN buffer from HeLa cells. Antibodies: Affinity purified rabbit anti-Selenoprotein S antibody NBP2-32096 used for IP at 6 ug per reaction. Selenoprotein S was also immunoprecipitated by rabbit anti-Selenoprotein S antibody BL16285. For blotting immunoprecipitated Selenoprotein S, NBP2-32096 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

SELS Antibody - H00055829-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SELS Antibody [H00055829-B01] - SELS MaxPab polyclonal antibody (B01), Lot # 07320WULz. Western Blot analysis of SELS expression in human placenta.

SELS Antibody - H00055829-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SELS Antibody [H00055829-B02P] - Analysis of SELS expression in A-431.

SELS Antibody - H00055829-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SELS Antibody [H00055829-B02] - SELS MaxPab polyclonal antibody. Western Blot analysis of SELS expression in A-431.

SELS Antibody - H00055829-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SELS Antibody [H00055829-D01P] - Analysis of SELS expression in HepG2.

SELS Polyclonal Antibody - bs-0277R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SELS Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0277R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SELS Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0277R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SELS Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0277R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SELS Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0277R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SELS Polyclonal Antibody, Cy3 Conjugated - bs-0277R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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