VIMP

Gene Symbol	VIMP
Entrez Gene	55829
Alt Symbol	AD-015, ADO15, SBBI8, SELS, SEPS1
Species	Human
Gene Type	protein-coding
Description	VCP-interacting membrane protein
Other Description	selenoprotein S
Swissprots	Q3B771 Q9P0I6 Q9BQE4
Accessions	EAX02295 Q9BQE4 AA487772 AF157317 AAF67483 AF328864 AAK15708 AI673590 AK026455 AK097011 AK225955 AK314723 AY324824 AAP85541 AY618665 AAT46592 BC005840 AAH05840 BC107774 AAI07775 BG829960 BI494034 BQ014190 BU740863 DQ578816 DW430970 NM_018445 NP_060915 NM_203472 NP_982298
Function	Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination. {ECO:0000269|PubMed:15215856}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm {ECO:0000250}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® VIMP siRNA II - 13818 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® VIMP siRNA I - 13803 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

Selenoprotein S CRISPR/Cas9 KO Plasmid (h) - sc-404444 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S HDR Plasmid (h) - sc-404444-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S Double Nickase Plasmid (h) - sc-404444-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S Double Nickase Plasmid (h2) - sc-404444-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S CRISPR Activation Plasmid (h) - sc-404444-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S CRISPR Activation Plasmid (h2) - sc-404444-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S Lentiviral Activation Particles (h) - sc-404444-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S Lentiviral Activation Particles (h2) - sc-404444-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Selenoprotein S siRNA (h) - sc-90187 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Selenoprotein S shRNA Plasmid (h) - sc-90187-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Selenoprotein S shRNA (h) Lentiviral Particles - sc-90187-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SELS RNAi - H00055829-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

SELS RNAi - H00055829-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU051821 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19060 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19060 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05404 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr05404

VIMP siRNA (Human) - CRJ0954 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

VIMP - MBS8203945 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human SELS (NM_203472.1) - SHH404160 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human SELS(NM_018445.4) - SHR213040 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human SELS(NM_203472.1) - SHR213312 from Creative biogene Category siRNA Species Reactivities Human

Human VIMP siRNA - orb271455 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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