Gene Symbol | PES1 |
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Entrez Gene | 23481 |
Alt Symbol | PES |
Species | Human |
Gene Type | protein-coding |
Description | pescadillo ribosomal biogenesis factor 1 |
Other Description | pescadillo homolog|pescadillo homolog 1, containing BRCT domain |
Swissprots | Q6IC29 O00541 |
Accessions | EAW59904 EAW59905 EAW59906 O00541 AB451380 BAG70194 AK096320 BAG53258 AK125778 BAC86285 AK127185 BAG54448 AK315518 BAG37899 AU098520 AU130886 BC032489 AAH32489 BQ576244 CR456539 CAG30425 CU013139 CAK54570 CU013427 CAK54869 U78310 AAB61140 XM_006724173 XP_006724236 NM_001243225 NP_001230154 NM_001282327 NP_001269256 NM_001282328 NP_001269257 NM_014303 NP_055118 |
Function | Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. {ECO:0000255|HAMAP-Rule:MF_03028, ECO:0000269|PubMed:16738141, ECO:0000269|PubMed:17189298, ECO:0000269|PubMed:17353269}. |
Subcellular Location | Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli. {ECO:0000255|HAMAP-Rule:MF_03028}. |
Tissue Specificity | Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin. |
Human PES1 ELISA Kit (Sandwich ELISA) - LS-F9972 from LifeSpan Bioscience
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Pescadillo Homolog 1 (PES1), ELISA Kit - MBS2025054 from MyBioSource
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pescadillo homolog 1, containing BRCT domain (zebrafish) , ELISA Kit - MBS9322721 from MyBioSource
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ELISA Kit for Pescadillo Homolog 1 (PES1) - SEK173Hu from Uscn Life Science Inc.
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Human PES1 ELISA Kit - E028788 from Biobool
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PES1 ELISA Kit (Human) (OKCD00595) - OKCD00595 from Aviva Systems Biology
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Human Pescadillo homolog (PES1) ELISA Kit - AE27991HU from ARP American Research Products
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Pescadillo Homolog (PES1), ELISA Kit - MBS9907250 from MyBioSource
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Pescadillo Homolog (PES1), ELISA Kit - MBS9907258 from MyBioSource
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