PES1

Gene Symbol PES1
Entrez Gene 23481
Alt Symbol PES
Species Human
Gene Type protein-coding
Description pescadillo ribosomal biogenesis factor 1
Other Description pescadillo homolog|pescadillo homolog 1, containing BRCT domain
Swissprots Q6IC29 O00541
Accessions EAW59904 EAW59905 EAW59906 O00541 AB451380 BAG70194 AK096320 BAG53258 AK125778 BAC86285 AK127185 BAG54448 AK315518 BAG37899 AU098520 AU130886 BC032489 AAH32489 BQ576244 CR456539 CAG30425 CU013139 CAK54570 CU013427 CAK54869 U78310 AAB61140 XM_006724173 XP_006724236 NM_001243225 NP_001230154 NM_001282327 NP_001269256 NM_001282328 NP_001269257 NM_014303 NP_055118
Function Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. {ECO:0000255|HAMAP-Rule:MF_03028, ECO:0000269|PubMed:16738141, ECO:0000269|PubMed:17189298, ECO:0000269|PubMed:17353269}.
Subcellular Location Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli. {ECO:0000255|HAMAP-Rule:MF_03028}.
Tissue Specificity Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.

pescadillo (C-17) - sc-48624 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
pescadillo (C-17): sc-48624. Western blot analysis of pescadillo expression in non-transfected: sc-117752 (A) and mouse pescadillo transfected: sc-125810 (B) 293T whole cell lysates.

pescadillo (H-10) - sc-166300 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
pescadillo (H-10): sc-166300. Western blot analysis of pescadillo expression in non-transfected 293T: sc-117752 (A), mouse pescadillo transfected 293T: sc-125810 (B) and HeLa (C) whole cell lysates.

pescadillo (H-300) - sc-134604 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

pescadillo (N-15) - sc-48626 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
pescadillo (N-15): sc-48626. Western blot analysis of pescadillo expression in HeLa whole cell lysate.

pescadillo (C-16) - sc-48623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
pescadillo (C-16): sc-48623. Western blot analysis of pescadillo expression in non-transfected: sc-110760 (A) and mouse pescadillo transfected: sc-111285 (B) 293 whole cell lysates.

Anti-Pescadillo antibody - ab129350 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab129350, at 2.5 - 3.75 µg/ml dilution, stains Pescadillo in Formalin/PFA-fixed paraffin-embedded human testis tissue by immunohistochemistry

Anti-Pescadillo antibody - ab19036 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Pescadillo antibody - ab88543 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Pescadillo antibody (ab88543) at 1 µg/ml + PC-12 cell lysate at 50 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-Pescadillo antibody - ab72539 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling Pescadillo with ab72539 at 1/200 (1µg/ml). Detection: DAB.

Anti-Pescadillo antibody - ab72537 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma (left) and ovarian carcinoma (right) tissues labelling Pescadillo with ab72537 at 1/1000 (1 µg/ml). Detection: DAB.

Anti-Pescadillo antibody - ab84512 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84512, at 1/250 dilution, staining Pescadillo in formalin-fixed, paraffin-embedded human breast adenocarcinoma by Immunohistochemistry, using DAB staining.

Anti-PES1 Antibody - LS-C90088 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (C-Terminus) - LS-C90090 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (aa549-578, AP) - LS-C216695 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (aa549-578, APC) - LS-C216696 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (aa549-578, Azide-free, HRP) - LS-C216699 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (aa549-578, Biotin) - LS-C216697 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (aa549-578, FITC) - LS-C216698 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (aa549-578, PE) - LS-C216702 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (aa549-578) - LS-C323935 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PES1 Antibody (C-Terminus) - LS-C81979 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PES1 Antibody (aa25-75) - LS-C287740 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Pescadillo by Immunohistochemistry. Sample: FFPE sections of human colon carcinoma (left) and ovarian carcinoma (right). Antibody: Affinity purified rabbit anti-Pescadillo used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-PES1 Antibody (aa475-525) - LS-C287483 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse Pescadillo By Western Blot. Samples: Lysate from BSC40 cells that were either mock transfected (1), transfected with WT Vaccinia virus (2), or transfected with Pescadillo expressing Vaccinia virus. Antibody: Rabbit anti-Pescadillo used at 1 ug/ml. Detection: Chemiluminescence.

Anti-PES1 Antibody (C-Terminus) - LS-C287741 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Pescadillo by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Pescadillo used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-PES1 Antibody (aa549-578) - LS-C158571 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PES1 Antibody western blot of U251 cell line lysates (35 ug/lane). The PES1 antibody detected the PES1 protein (arrow).
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