CD55

Gene Symbol	CD55
Entrez Gene	1604
Alt Symbol	CR, CROM, DAF, TC
Species	Human
Gene Type	protein-coding
Description	CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Other Description	CD55 antigen|complement decay-accelerating factor
Swissprots	D3DT84 P78361 Q14UF3 B1AP14 P09679 Q14UF4 D3DT83 Q14UF2 Q14UF5 E7ER69 Q14UF6 P08174
Accessions	AAA52170 AAC60633 AAW29942 BAA22900 CBX47421 EAW93485 EAW93486 EAW93487 EAW93488 EAW93489 EAW93490 EAW93491 EAW93492 EAW93493 EAW93494 EAW93495 EAW93496 EAW93497 EAW93498 EAW93499 P08174 AB240566 BAE97422 AB240567 BAE97423 AB240568 BAE97424 AB240569 BAE97425 AB240570 BAE97426 AF052110 AK298549 BAG60746 AK300621 BAG62314 AK312448 BAG35355 AW316643 AY055757 AAL25832 AY055758 AAL25833 AY055759 AAL25834 AY055760 AAL25835 BC001288 AAH01288 BI545505 BT007159 AAP35823 CA432400 CA748776 DC386415 DQ890776 ABM81702 DQ893935 ABM84861 M15799 AAA52167 M30142 AAA52168 M31516 AAA52169 S70688 AAB20576 U88576 AAB48622 NM_000574 NP_000565 NM_001114752 NP_001108224 NM_001300902 NP_001287831 NM_001300903 NP_001287832 NM_001300904 NP_001287833 NR_125349 NM_001114543 NM_001114544
Function	This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. {ECO:0000269|PubMed:7525274}.
Subcellular Location	Isoform 7: Cell membrane {ECO:0000305|PubMed:16503113}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:16503113}.
Tissue Specificity	Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
Top Pathways	Complement and coagulation cascades, Hematopoietic cell lineage

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD55 ELISA Kit (Sandwich ELISA) - LS-F5298 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 13.5 pg/ml Range 31.25-2000 pg/ml

Human CD55 ELISA Kit (Sandwich ELISA) - LS-F11277 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 31.25-2000 pg/ml

Human DAF ELISA Kit - abx151250 from Abbexa Category ELISA Kit Sensitivity 14.7 pg/ml Range 31.25 pg/ml - 2000 pg/ml

Complement decay-accelerating factor, CD55, Human, ELISA Kit - E0468h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 31.2-2000 pg/mL

Decay Accelerating Factor, DAF, Human, ELISA Kit - E-EL-H1950 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Decay Accelerating Factor, DAF, Rat, ELISA Kit - E-EL-R0320 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Decay Accelerating Factor, DAF, Rabbit, ELISA Kit - E-EL-RB1119 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Decay Accelerating Factor, DAF, Chicken, ELISA Kit - E-EL-Ch1106 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Decay Accelerating Factor, DAF, Porcine, ELISA Kit - E-EL-P0136 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Decay Accelerating Factor, DAF, Sheep, ELISA Kit - E-EL-S0220 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Decay Accelerating Factor, DAF, Guinea Pig, ELISA Kit - E-EL-GP1268 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Decay Accelerating Factor, DAF, Monkey, ELISA Kit - E-EL-MK0837 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

CD55 (Human) Matched Antibody Pair - H00001604-AP41 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

CD55 (Human) Matched Antibody Pair - H00001604-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Custom Human CD55 ELISA - ELH-CD55 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human TC ELISA Kit - HT0027 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine TC ELISA Kit - AT0027 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Decay Accelerating Factor (DAF), ELISA Kit - MBS2020810 from MyBioSource Category ELISA Kit Prices $345.00, $515.00, $695.00, $2,840.00, $5,180.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 13.5pg/mL. Range 31.25-2000pg/mL

ELISA Kit for Decay Accelerating Factor (DAF) - SEA468Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 13.5pg/mL. Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA’s were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

Human DAF(Decay Accelerating Factor) ELISA Kit - E-EL-H1950 from Elabscience Category ELISA Kit Sensitivity 18.75 pg/mL Range 31.25—2000 pg/mL

Human DAF (Decay Accelerating Factor) CLIA Kit - E-CL-H1198 from Elabscience Category CLIA Kit Sensitivity 7.50 pg/mL Range Average Recovery (%)

CD55 molecule, decay accelerating factor for complement (Cromer blood group) , ELISA Kit - MBS703778 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human DAF/CD55 is typically less than 0.156 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.6 25 ng/ml -40 ng/ml.

DAF, ELISA Kit - MBS2514716 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

DAF, ELISA Kit - MBS2513733 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

DAF, ELISA Kit - MBS2501193 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

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