CD55

Gene Symbol	CD55
Entrez Gene	1604
Alt Symbol	CR, CROM, DAF, TC
Species	Human
Gene Type	protein-coding
Description	CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Other Description	CD55 antigen|complement decay-accelerating factor
Swissprots	D3DT84 P78361 Q14UF3 B1AP14 P09679 Q14UF4 D3DT83 Q14UF2 Q14UF5 E7ER69 Q14UF6 P08174
Accessions	AAA52170 AAC60633 AAW29942 BAA22900 CBX47421 EAW93485 EAW93486 EAW93487 EAW93488 EAW93489 EAW93490 EAW93491 EAW93492 EAW93493 EAW93494 EAW93495 EAW93496 EAW93497 EAW93498 EAW93499 P08174 AB240566 BAE97422 AB240567 BAE97423 AB240568 BAE97424 AB240569 BAE97425 AB240570 BAE97426 AF052110 AK298549 BAG60746 AK300621 BAG62314 AK312448 BAG35355 AW316643 AY055757 AAL25832 AY055758 AAL25833 AY055759 AAL25834 AY055760 AAL25835 BC001288 AAH01288 BI545505 BT007159 AAP35823 CA432400 CA748776 DC386415 DQ890776 ABM81702 DQ893935 ABM84861 M15799 AAA52167 M30142 AAA52168 M31516 AAA52169 S70688 AAB20576 U88576 AAB48622 NM_000574 NP_000565 NM_001114752 NP_001108224 NM_001300902 NP_001287831 NM_001300903 NP_001287832 NM_001300904 NP_001287833 NR_125349 NM_001114543 NM_001114544
Function	This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. {ECO:0000269|PubMed:7525274}.
Subcellular Location	Isoform 7: Cell membrane {ECO:0000305|PubMed:16503113}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:16503113}.
Tissue Specificity	Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
Top Pathways	Complement and coagulation cascades, Hematopoietic cell lineage

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CD55 full length protein - ab168708 from Abcam Category Protein Prices $352.00 Sizes 100 µg Source HEK 293 cells Species Human

Human CD55 full length protein - ab151340 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human CD55 protein fragment - ab80038 from Abcam Category Protein Prices $188.00 Sizes 250 µg Source E. coli Species Human

CD55 Antibody Blocking Peptide - LS-E3596 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD55 Antibody Blocking Peptide - LS-E22028 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD55/DAF Recombinant Protein - H00001604-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CD55/DAF Partial Recombinant Protein - H00001604-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CD55-Antibody-N-term-Blocking-Peptide - BP14798a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human CD55/DAF - 2009-CD-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human CD55/DAF, CF - 2009-CD-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human CD55 His tag protein - orb83521 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human CD55 protein - orb49158 from Biorbyt Category Protein Prices $272.00, $366.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human CD55 Fc tag protein - orb82905 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

CD55 Blocking Peptide - 33R-7141 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CD55 / DAF - H00001604-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD55 / DAF - H00001604-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CD55 / DAF - H00001604-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD55 / DAF - H00001604-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD55, Human, Recombinant - 19-C323 from ARP American Research Products Category Protein Prices $109.00 Sizes 10 µg Source HEK293 Species Human

DAF Peptide - 7937P from ProSci Category Peptide Species Human

CD55 Recombinant Protein - 96-117 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

Recombinant Human CD55 Protein - BP001667-C323 from Syd Labs Category Protein Prices $98.00, $264.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source HEK 293-derived. Species Human

Recombinant Human CD55, Fc tagged - CD55-64H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human CD55, His tagged - CD55-2223H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human CD55, His-tagged - CD55-26634TH from Creative Biomart Category Protein Source E. coli

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