FCHO1

Gene Symbol FCHO1
Entrez Gene 23149
Alt Symbol -
Species Human
Gene Type protein-coding
Description FCH domain only 1
Other Description F-BAR domain only protein 1|FCH domain only protein 1
Swissprots A6NHE6 Q05C93 Q8IW22 B4E120 O14526 A8K5U5
Accessions CAD35013 EAW84628 EAW84629 EAW84630 O14526 AB006628 BAA22959 AK291410 BAF84099 AK303623 BAG64632 AK309403 AK316458 BAH14829 BC028021 AAH28021 BC041130 AAH41130 BI756664 BQ433639 DB158605 XM_005259831 XP_005259888 XM_006722701 XP_006722764 XM_006722702 XP_006722765 XM_011527824 XP_011526126 XM_011527825 XP_011526127 XM_011527826 XP_011526128 XM_011527827 XP_011526129 XM_011527828 XP_011526130 NM_001161357 NP_001154829 NM_001161358 NP_001154830 NM_001161359 NP_001154831 NM_015122 NP_055937
Function Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors. {ECO:0000269|PubMed:20448150}.
Subcellular Location Membrane, clathrin-coated pit {ECO:0000305|PubMed:17617719, ECO:0000305|PubMed:20448150}; Peripheral membrane protein {ECO:0000305|PubMed:17617719, ECO:0000305|PubMed:20448150}; Cytoplasmic side {ECO:0000305|PubMed:17617719, ECO:0000305|PubMed:20448150}. Note=Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2. According to PubMed:17617719 it may also dynamically associate with Golgi/TGN membranes.

FCHO1 (G-7) - sc-365043 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FCHO1 (G-7): sc-365043. Western blot analysis of FCHO1 expression in K-562 whole cell lysate.

FCHO1 (H-129) - sc-98625 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FCHO1 (H-129): sc-98625. Western blot analysis of FCHO1 expression in non-transfected: sc-117752 (A) and mouse FCHO1 transfected: sc-120228 (B) 293T whole cell lysates.

FCHO1 (P-16) - sc-103492 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FCHO1 antibody - ab84740 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-FCHO1 antibody (ab84740) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-FCHO1 antibody - ab102994 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab102994 stained PANC-1 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab102994 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-FCHO1 Antibody (aa19-194) - LS-C179113 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FCHO1 Antibody (aa468-517) IHC-plus™ - LS-B3998 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FCHO1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3998 concentration 5 ug/ml.

FCHO1 Antibody - NBP2-16458 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FCHO1 Antibody [NBP2-16458] - A: U87-MG.

FCHO1 Antibody - NBP1-79578 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FCHO1 Antibody [NBP1-79578] - 293T Cell Lysate 1ug/ml Gel Concentration 12%

FCHO1 Antibody - NBP2-16459 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FCHO1 Antibody [NBP2-16459] - Sample (30 ug of whole cell lysate) A: Raji 7. 5% SDS PAGE gel, diluted at 1:1000.

FCHO1 Polyclonal Antibody - bs-13152R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13152R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13152R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13152R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13152R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, Cy3 Conjugated - bs-13152R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, Cy5 Conjugated - bs-13152R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, Cy5.5 Conjugated - bs-13152R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, Cy7 Conjugated - bs-13152R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, FITC Conjugated - bs-13152R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, Biotin Conjugated - bs-13152R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FCHO1 Polyclonal Antibody, HRP Conjugated - bs-13152R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FCHO1 antibody produced in rabbit - HPA041653 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FCHO1: <B>Cat. No. HPA041653</B>: Immunohistochemical staining of human colon shows moderate cytoplasmic, nuclear and membranous positivity in glandular cells.

Anti-FCHO1 (N-terminal) antibody produced in rabbit - SAB2701439 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FCHO1 (N-terminal): <B>Cat. No. SAB2701439</B>: Immunohistochemical analysis of paraffin-embedded cal27 xenograft, using FCHO1 antibody at 1:500 dilution.

Anti-FCHO1 antibody produced in rabbit - SAB2100803 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FCHO1: <B>Cat. No. SAB2100803</B>: Immunohistochemistry of FCHO1 in Human Spleen tissue with FCHO1 antibody at 5.0 μg/mL.
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