DCXR

Gene Symbol	DCXR
Entrez Gene	51181
Alt Symbol	DCR, HCR2, HCRII, KIDCR, P34H, PNTSU, SDR20C1, XR
Species	Human
Gene Type	protein-coding
Description	dicarbonyl/L-xylulose reductase
Other Description	L-xylulose reductase|carbonyl reductase 2|carbonyl reductase II|kidney dicarbonyl reductase|short chain dehydrogenase/reductase family 20C member 1|short chain dehydrogenase/reductase family 20C, member 1|sperm surface protein P34H
Swissprots	Q9BTZ3 Q9UHY9 Q7Z4W1
Accessions	EAW89732 EAW89733 Q7Z4W1 AA446582 AB013846 BAB64299 AF113123 AAF14864 AF139841 AAP97273 AF515623 AAN59786 AF515624 AAO15991 AF515625 AAM54026 AK226040 AV653537 BC001470 AAH01470 BC003018 AAH03018 BG434209 BT006881 AAP35527 CB959852 NM_001195218 NP_001182147 NM_016286 NP_057370
Function	Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Subcellular Location	Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Probably recruited to membranes via an interaction with phosphatidylinositol. {ECO:0000250}.
Tissue Specificity	Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis. {ECO:0000269|PubMed:10385429, ECO:0000269|PubMed:11882650}.
Top Pathways	Pentose and glucuronate interconversions

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DCXR full length protein - ab98147 from Abcam Category Protein Source E. coli Species Human

Human DCXR full length protein - ab117694 from Abcam Category Protein Source E. coli Species Human

DCXR Antibody Blocking Peptide - LS-E25388 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DCXR Antibody Blocking Peptide - LS-E8957 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DCXR Antibody Blocking Peptide - LS-E15633 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DCXR Partial Recombinant Protein - H00051181-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DCXR Recombinant Protein - H00051181-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human DCXR Protein - NBP1-50835 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

DCXR-Antibody-Center-Blocking-Peptide - BP7443c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DCXR blocking peptide - GTX11800-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

DCXR Protein (OPPA02288) - OPPA02288 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human DCXR protein (His Tag) - orb138688 from Biorbyt Category Protein Prices $298.00, $612.00 Sizes 20 μg, 100 μg Source E. coli Species Human

DCXR Immunizing peptide - orb17535 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

DCXR Blocking Peptide - 33R-8869 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

DCXR protein (His tag) - 80R-1381 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

DCXR Peptide - AC21-0216-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

L-xylulose reductase (1-244, His-tag) - AR09555PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

L-xylulose reductase (1-244, His-tag) - AR09555PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

L-xylulose reductase - H00051181-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

L-xylulose reductase - H00051181-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

L-xylulose reductase - H00051181-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

L-xylulose reductase - H00051181-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Dicarbonyl/L-Xylulose Reductase, Human Recombinant - 228-12557-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Dicarbonyl/L-Xylulose Reductase Human - 228-12557-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Dicarbonyl/L-Xylulose Reductase Human - 228-12557-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

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