Gene Symbol | TIGAR |
---|---|
Entrez Gene | 57103 |
Alt Symbol | C12orf5, FR2BP |
Species | Human |
Gene Type | protein-coding |
Description | TP53 induced glycolysis regulatory phosphatase |
Other Description | TP53-induced glycolysis and apoptosis regulator|fructose-2,6-bisphosphatase TIGAR|fructose-2,6-bisphosphate 2-phosphatase|probable fructose-2,6-bisphosphatase TIGAR|transactivated by NS3TP2 protein |
Swissprots | Q9NQ88 B2R840 |
Accessions | EAW88849 EAW88850 Q9NQ88 AJ272206 CAC01127 AK313226 BAG36037 AM392615 CAL37493 AY425618 AAQ98969 BC012340 AAH12340 BX098281 DB480618 NM_020375 NP_065108 |
Function | Fructose-bisphosphatase hydrolyzing fructose-2,6- bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6- bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53. {ECO:0000269|PubMed:16839880}. |
Top Pathways | Central carbon metabolism in cancer, Fructose and mannose metabolism |
Human Probable fructose-2,6-bisphosphatase TIGAR ELISA Kit - EKE54207 from Biomatik
|
||||||||||
Human TIGAR ELISA Kit - E030784 from Biobool
|
||||||||||
TIGAR ELISA Kit (Human) (OKEH03298) - OKEH03298 from Aviva Systems Biology
|
||||||||||
Human Probable fructose-2,6-bisphosphatase TIGAR ELISA Kit - EK4701 from Signalway Antibody
|
||||||||||
Probable fructose-2, 6-bisphosphatase TIGAR, ELISA Kit - MBS9428527 from MyBioSource
|
||||||||||
Probable fructose-2,6-bisphosphatase TIGAR, ELISA Kit - MBS2887830 from MyBioSource
|