TIGAR

Gene Symbol TIGAR
Entrez Gene 57103
Alt Symbol C12orf5, FR2BP
Species Human
Gene Type protein-coding
Description TP53 induced glycolysis regulatory phosphatase
Other Description TP53-induced glycolysis and apoptosis regulator|fructose-2,6-bisphosphatase TIGAR|fructose-2,6-bisphosphate 2-phosphatase|probable fructose-2,6-bisphosphatase TIGAR|transactivated by NS3TP2 protein
Swissprots Q9NQ88 B2R840
Accessions EAW88849 EAW88850 Q9NQ88 AJ272206 CAC01127 AK313226 BAG36037 AM392615 CAL37493 AY425618 AAQ98969 BC012340 AAH12340 BX098281 DB480618 NM_020375 NP_065108
Function Fructose-bisphosphatase hydrolyzing fructose-2,6- bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6- bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53. {ECO:0000269|PubMed:16839880}.
Top Pathways Central carbon metabolism in cancer, Fructose and mannose metabolism

TIGAR CRISPR/Cas9 KO Plasmid (h) - sc-401390 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR HDR Plasmid (h) - sc-401390-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR Double Nickase Plasmid (h) - sc-401390-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR Double Nickase Plasmid (h2) - sc-401390-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR CRISPR Activation Plasmid (h) - sc-401390-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR CRISPR Activation Plasmid (h2) - sc-401390-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR Lentiviral Activation Particles (h) - sc-401390-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR Lentiviral Activation Particles (h2) - sc-401390-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIGAR siRNA (h) - sc-76662 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIGAR shRNA Plasmid (h) - sc-76662-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIGAR shRNA (h) Lentiviral Particles - sc-76662-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU006891 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4260 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4260 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TIGAR siRNA (Human) - CRJ1323 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TIGAR - MBS8207970 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C12orf5 (NM_020375.2) - SHH249126 from Creative biogene

Category siRNA
Species Reactivities Human

Human TIGAR siRNA - orb271824 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TIGAR shRNA Plasmid (Human) - CHJ1323 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C12ORF5 miRNA 3'UTR clone - MiUTR1H-01067 from Creative biogene

Species Reactivities Human
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