BMPR1A

Gene Symbol	BMPR1A
Entrez Gene	657
Alt Symbol	10q23del, ACVRLK3, ALK3, CD292, SKR5
Species	Human
Gene Type	protein-coding
Description	bone morphogenetic protein receptor, type IA
Other Description	ALK-3|BMP type-1A receptor|BMPR-1A|activin A receptor, type II-like kinase 3|activin receptor-like kinase 3|bone morphogenetic protein receptor type-1A|serine/threonine-protein kinase receptor R5
Swissprots	Q8NEN8 A8K6U9 P36894
Accessions	CBY84973 EAW80320 P36894 AB451405 BAG70219 AK291764 BAF84453 BC028383 AAH28383 BM819272 DQ786215 DQ891524 ABM82450 DQ894714 ABM85640 Z22535 CAA80257 XM_011540103 XP_011538405 XM_011540104 XP_011538406 NM_004329 NP_004320
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in skeletal muscle.
Top Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BMPR-IA CRISPR/Cas9 KO Plasmid (h) - sc-400581 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA HDR Plasmid (h) - sc-400581-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA Double Nickase Plasmid (h) - sc-400581-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA Double Nickase Plasmid (h2) - sc-400581-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA CRISPR Activation Plasmid (h) - sc-400581-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA CRISPR Activation Plasmid (h2) - sc-400581-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA Lentiviral Activation Particles (h) - sc-400581-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA Lentiviral Activation Particles (h2) - sc-400581-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BMPR-IA siRNA (h) - sc-40216 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BMPR-IA shRNA Plasmid (h) - sc-40216-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BMPR-IA shRNA (h) Lentiviral Particles - sc-40216-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BMPR-IA/ALK-3 RNAi - H00000657-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU105981 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0172 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0170 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0171 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2207 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2207 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09651 from Sigma-Aldrich Category miRNA

BMPR1A siRNA (Human) - CRH0452 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

BMPR1A - MBS8216639 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human BMPR1A(NM_004329.2) - SHG102257 from Creative biogene Category siRNA Species Reactivities Human

BMPR1A shRNA Plasmid (Human) - CHH0452 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

BMPR1A miRNA 3'UTR clone - MiUTR3H-04045 from Creative biogene Species Reactivities Human

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