BMPR1A

Gene Symbol BMPR1A
Entrez Gene 657
Alt Symbol 10q23del, ACVRLK3, ALK3, CD292, SKR5
Species Human
Gene Type protein-coding
Description bone morphogenetic protein receptor, type IA
Other Description ALK-3|BMP type-1A receptor|BMPR-1A|activin A receptor, type II-like kinase 3|activin receptor-like kinase 3|bone morphogenetic protein receptor type-1A|serine/threonine-protein kinase receptor R5
Swissprots Q8NEN8 A8K6U9 P36894
Accessions CBY84973 EAW80320 P36894 AB451405 BAG70219 AK291764 BAF84453 BC028383 AAH28383 BM819272 DQ786215 DQ891524 ABM82450 DQ894714 ABM85640 Z22535 CAA80257 XM_011540103 XP_011538405 XM_011540104 XP_011538406 NM_004329 NP_004320
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in skeletal muscle.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

BMPR-I (H-45) - sc-25454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BMPR-I (H-45): sc-25454. Western blot analysis of BMPR-I expression in c4 whole cell lysate.

BMPR-I (C-16) - sc-5678 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BMPR-IA (H-60) - sc-20736 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BMPR-IA (H-60): sc-20736. Western blot analysis of BMPR-IA expression in HeLa (A) and Jurkat (B) whole cell lysates.

BMPR-IA (E-16) - sc-5676 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BMPR-IA (E-16): sc-5676. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic staining of myocytes cells.

BMPR-IA (7K7) - sc-134285 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
BMPR-IA (7K7): sc-134285. Western blot analysis of BMPR-IA expression in human BMPR-IA transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-BMPR1A antibody - ab38560 from Abcam

Prices $385.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical (formalin/PFA-fixed paraffin-embedded sections) analysis of human hepatocarcinoma tissue labelling BMPR1A with ab38560. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0.5 hour at 38°C. Antigen retrieval was heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A peroxidase-conjugated goat anti-rabbit polyclonal (ready to use) was used as the secondary antibody.

Anti-BMPR1A antibody - ab59947 from Abcam

Prices $382.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BMPR1A antibody (ab59947) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : K562 cell lysateLane 3 : MCF7 cell lysateLane 4 : Human liver tissue lysateLane 5 : Mouse liver tissue lysateLysates/proteins at 35 µg per lane.SecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-BMPR1A antibody - ab174815 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of TBMPR1A staining in Normal human heart muscle formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab174815, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times. 

Anti-BMPR1A antibody - ab59945 from Abcam

Prices $385.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab59945 at 1/50 - 1/100 dilution, staining BMPR1A in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.

Anti-BMPR1A antibody - ab77022 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-BMPR1A antibody (ab77022) at 5 µg/ml + recombinant full length BMPR1A protein (the immunogen) at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-BMPR1A antibody - ab52023 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-BMPR1A antibody (ab52023) at 1 µg/ml + HeLa cell lysate (35µg protein in RIPA buffer).

Anti-BMPR1A antibody [4B7B2] - ab166707 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4B7B2
Anti-BMPR1A antibody [4B7B2] (ab166707) at 1/500 dilution + Recombinant Human BMPR1A protein

Anti-BMPR1A antibody - Aminoterminal end - ab70988 from Abcam

Prices $379.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-BMPR1A antibody - Aminoterminal end (ab70988) at 1/100 dilution + Saos2 cell lysate at 12.5 µgSecondaryHRP-conjugated anti-rabbit developed using the ECL technique

Anti-BMPR1A antibody - Azide free - ab189930 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BMPR1A antibody - Azide free (ab189930) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : K562 cell lysateLane 3 : MCF-7 cell lysateLane 4 : Human liver tissue lysateLane 5 : Mouse liver tissue lysateLysates/proteins at 35 µg per lane.SecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-BMPR1A antibody - N-terminal - ab191450 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-BMPR1A antibody - N-terminal (ab191450) at 0.5 µg/ml + Rat testis lysate

Anti-ALK3 / BMPR1A Antibody (aa36-51) - LS-C3035 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALK3 / BMPR1A Antibody (Internal) - LS-C4216 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALK3 / BMPR1A Antibody (aa1-533) - LS-C127073 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ALK3 / BMPR1A Antibody (aa36-46) - LS-C54585 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of HeLa cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-ALK3 / BMPR1A Antibody (APC) - LS-C182770 from LifeSpan Bioscience

Prices $635.00
Sizes 100 tst
Host Goat
Clonality Polyclonal

Anti-ALK3 / BMPR1A Antibody (Extracellular Domain) - LS-C190051 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ALK3 / BMPR1A Antibody (aa169-197, AP) - LS-C252618 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALK3 / BMPR1A Antibody (aa169-197, APC) - LS-C252619 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALK3 / BMPR1A Antibody (aa169-197, Biotin) - LS-C252620 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ALK3 / BMPR1A Antibody (aa169-197, FITC) - LS-C252621 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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