Gene Symbol | TCEAL7 |
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Entrez Gene | 56849 |
Alt Symbol | MPMGp800C04260Q003, WEX5 |
Species | Human |
Gene Type | protein-coding |
Description | transcription elongation factor A (SII)-like 7 |
Other Description | TCEA-like protein 7|transcription elongation factor A protein-like 7|transcription elongation factor S-II protein-like 7 |
Swissprots | B3KSV2 Q9BRU2 Q96AT4 |
Accessions | EAW54714 Q9BRU2 AJ297363 CAB95948 AK094400 BAG52864 BC005988 AAH05988 BC016786 AAH16786 DA142141 DB481725 EU446610 ABZ92139 EU446623 ABZ92152 NM_152278 NP_689491 |
Function | Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines. {ECO:0000269|PubMed:18806825, ECO:0000269|PubMed:19966855, ECO:0000269|PubMed:20454512}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18806825}. |
Tissue Specificity | Highly expressed in normal and fetal brain tissues, and weakly expressed in uterus and ovary. Down-regulated in epithelial ovarian, cervical, prostate, breast, brain and lung cancer cell lines and in brain and ovarian tumors. {ECO:0000269|PubMed:18806825}. |
TCEAL7 (C-12) - sc-240963 from Santa Cruz Biotechnology
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TCEAL7 (E-14) - sc-240961 from Santa Cruz Biotechnology
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Anti-TCEAL7 antibody - ab122945 from Abcam
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Anti-TCEAL7 Antibody (aa40-89) - LS-C146100 from LifeSpan Bioscience
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TCEAL7 Antibody - NBP2-30974 from Novus Biologicals
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Anti-TCEAL7 antibody produced in rabbit - HPA051507 from Sigma-Aldrich
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TCEAL7 antibody - 70R-20733 from Fitzgerald
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Transcription Elongation Factor A (Sii)-Like 7 Antibody - abx116149 from Abbexa
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TCEAL7 antibody - 11218-1-AP from Acris Antibodies
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TCEAL7 antibody - 11218-1-AP from Proteintech Group
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TCEAL7 Antibody - CSB-PA023278GA01HU from Cusabio
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TCEAL7, Polyclonal Antibody - MBS5300648 from MyBioSource
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TCEAL7 - A8696 from NeoScientific
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TCEAL7 Polyclonal Antibody - A8696 from ABclonal
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TCEAL7 Antibody,HRP conjugated - CSB-PA863109LB01HU from Cusabio
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TCEAL7 Antibody,FITC conjugated - CSB-PA863109LC01HU from Cusabio
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TCEAL7 Antibody,Biotin conjugated - CSB-PA863109LD01HU from Cusabio
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TCEAL7 Antibody - CSB-PA863109LA01HU from Cusabio
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TCEAL7 Antibody - abx124717 from Abbexa
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TCEAL7 antibody - orb357063 from Biorbyt
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TCEAL7 Antibody - 46283 from Signalway Antibody
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TCEAL7 Antibody - DF9969 from Affinity Biosciences
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anti-TCEAL7 antibody - A008547 from Biobool
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Anti-TCEAL7 Antibody (HRP) - LS-C379324 from LifeSpan Bioscience
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Anti-TCEAL7 Antibody - LS-C410228 from LifeSpan Bioscience
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