TCEAL7

Gene Symbol TCEAL7
Entrez Gene 56849
Alt Symbol MPMGp800C04260Q003, WEX5
Species Human
Gene Type protein-coding
Description transcription elongation factor A (SII)-like 7
Other Description TCEA-like protein 7|transcription elongation factor A protein-like 7|transcription elongation factor S-II protein-like 7
Swissprots B3KSV2 Q9BRU2 Q96AT4
Accessions EAW54714 Q9BRU2 AJ297363 CAB95948 AK094400 BAG52864 BC005988 AAH05988 BC016786 AAH16786 DA142141 DB481725 EU446610 ABZ92139 EU446623 ABZ92152 NM_152278 NP_689491
Function Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines. {ECO:0000269|PubMed:18806825, ECO:0000269|PubMed:19966855, ECO:0000269|PubMed:20454512}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18806825}.
Tissue Specificity Highly expressed in normal and fetal brain tissues, and weakly expressed in uterus and ovary. Down-regulated in epithelial ovarian, cervical, prostate, breast, brain and lung cancer cell lines and in brain and ovarian tumors. {ECO:0000269|PubMed:18806825}.

TCEAL7 CRISPR/Cas9 KO Plasmid (h) - sc-418186 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 HDR Plasmid (h) - sc-418186-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 Double Nickase Plasmid (h) - sc-418186-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 Double Nickase Plasmid (h2) - sc-418186-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 CRISPR Activation Plasmid (h) - sc-418186-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 CRISPR Activation Plasmid (h2) - sc-418186-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 Lentiviral Activation Particles (h) - sc-418186-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 Lentiviral Activation Particles (h2) - sc-418186-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TCEAL7 siRNA (h) - sc-91253 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TCEAL7 shRNA Plasmid (h) - sc-91253-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TCEAL7 shRNA (h) Lentiviral Particles - sc-91253-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TCEAL7 RNAi - H00056849-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU084181 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21128 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21128 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05506 from Sigma-Aldrich

Category miRNA

TCEAL7 siRNA (Human) - CRJ1186 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TCEAL7 - MBS827956 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TCEAL7 (NM_152278.3) - SHH424628 from Creative biogene

Category siRNA
Species Reactivities Human

TCEAL7 shRNA Plasmid (Human) - CHJ1186 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TCEAL7 miRNA 3'UTR clone - MiUTR3H-02934 from Creative biogene

Species Reactivities Human
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