Gene Symbol | GPR119 |
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Entrez Gene | 139760 |
Alt Symbol | GPCR2 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 119 |
Other Description | G-protein coupled receptor 2|glucose-dependent insulinotropic receptor |
Swissprots | Q4VBN3 Q8TDV5 Q495H7 |
Accessions | BAB89297 BAC06151 CAM84963 Q8TDV5 AY288416 AAP72125 BC095502 AAH95502 BC101166 AAI01167 BC101167 AAI01168 BC101168 AAI01169 BC126179 AAI26180 BC126181 AAI26182 HQ258187 ADR82941 NM_178471 NP_848566 |
Function | Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. {ECO:0000269|PubMed:16517404}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominantly expressed in the pancreas, especially in the islets. {ECO:0000269|PubMed:15607732}. |
Top Pathways | cAMP signaling pathway |
GPCR GPR119 peptide - ab138476 from Abcam
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GPR119 Blocking Peptide - LS-E29069 from LifeSpan Bioscience
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GPR119 Antibody Blocking Peptide - LS-E29070 from LifeSpan Bioscience
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GPR119 Blocking Peptide - LS-E29073 from LifeSpan Bioscience
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GPR119 Antibody Blocking Peptide - LS-E29071 from LifeSpan Bioscience
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GPR119 Antibody Blocking Peptide - LS-E26756 from LifeSpan Bioscience
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GPR119 Peptide - NB110-92716PEP from Novus Biologicals
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GPR119 blocking peptide - GTX88703-PEP from GeneTex
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GPCR GPR119 Peptide - AC21-1592-P from Abcore
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GPR119 - H00139760-G01 from Acris Antibodies
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GPR119 - H00139760-Q01-10 from Acris Antibodies
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GPR119 - H00139760-Q01-25 from Acris Antibodies
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GPR119 Peptide - 45-692P from ProSci
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GPR119 fusion protein - ag19455 from Proteintech Group
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GPR119 fusion protein - ag19693 from Proteintech Group
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GPR119 Blocking Peptide - CBP3970 from Cohesion Biosciences
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GPR119 (V227) Peptide - BS2606P from Bioworld Technology
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Recombinant Human GPR119 Protein - H00139760-G01 from Novus Biologicals
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GPR119, Peptide - MBS425454 from MyBioSource
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GPR119 Blocking Peptide - abx162463 from Abbexa
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GPR119 Peptide, Human - M34GP06517H from Creative Peptides
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GPR119 Immunizing peptide - orb16207 from Biorbyt
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Glucose-dependent insulinotropic receptor (GPR119), Recombinant Protein - MBS7016068 from MyBioSource
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GPR119 peptide - orb256857 from Biorbyt
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