Gene Symbol | GPR119 |
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Entrez Gene | 139760 |
Alt Symbol | GPCR2 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 119 |
Other Description | G-protein coupled receptor 2|glucose-dependent insulinotropic receptor |
Swissprots | Q4VBN3 Q8TDV5 Q495H7 |
Accessions | BAB89297 BAC06151 CAM84963 Q8TDV5 AY288416 AAP72125 BC095502 AAH95502 BC101166 AAI01167 BC101167 AAI01168 BC101168 AAI01169 BC126179 AAI26180 BC126181 AAI26182 HQ258187 ADR82941 NM_178471 NP_848566 |
Function | Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. {ECO:0000269|PubMed:16517404}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominantly expressed in the pancreas, especially in the islets. {ECO:0000269|PubMed:15607732}. |
Top Pathways | cAMP signaling pathway |
GPR119 (K-16) - sc-48195 from Santa Cruz Biotechnology
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GPR119 (H-100) - sc-99103 from Santa Cruz Biotechnology
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Anti-GPCR GPR119 antibody - ab75312 from Abcam
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Anti-GPCR GPR119 antibody - ab77391 from Abcam
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Anti-GPCR GPR119 antibody - ab189041 from Abcam
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Anti-GPR119 Antibody (Biotin) - LS-C182029 from LifeSpan Bioscience
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Anti-GPR119 Antibody (DY650) - LS-C182030 from LifeSpan Bioscience
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Anti-GPR119 Antibody (DY488) - LS-C182031 from LifeSpan Bioscience
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Anti-GPR119 Antibody (DY550) - LS-C182032 from LifeSpan Bioscience
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Anti-GPR119 Antibody (Val227) - LS-C177093 from LifeSpan Bioscience
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Anti-GPR119 Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A549 from LifeSpan Bioscience
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Anti-GPR119 Antibody (Internal) IHC-plus™ - LS-A546 from LifeSpan Bioscience
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Anti-GPR119 Antibody (aa186-235) IHC-plus⢠- LS-B6791 from LifeSpan Bioscience
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Anti-GPR119 Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A548 from LifeSpan Bioscience
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Anti-GPR119 Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A547 from LifeSpan Bioscience
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Anti-GPR119 Antibody (aa309-322) - LS-C54930 from LifeSpan Bioscience
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Anti-GPR119 Antibody (C-Terminus) - LS-C144833 from LifeSpan Bioscience
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Anti-GPR119 Antibody (C-Terminus) - LS-C144991 from LifeSpan Bioscience
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GPR119 Antibody - NLS548 from Novus Biologicals
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GPR119 Antibody - NBP1-44327 from Novus Biologicals
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GPR119 Antibody - NBP1-00857 from Novus Biologicals
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GPR119 Antibody - NB100-94884 from Novus Biologicals
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GPR119 Antibody [DyLight 488] - NLS548G from Novus Biologicals
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GPR119 Antibody [DyLight 650] - NLS548C from Novus Biologicals
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GPR119 Antibody [Biotin] - NLS548B from Novus Biologicals
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