VTA1

Gene Symbol VTA1
Entrez Gene 51534
Alt Symbol C6orf55, DRG-1, DRG1, HSPC228, LIP5, My012, SBP1
Species Human
Gene Type protein-coding
Description vesicle (multivesicular body) trafficking 1
Other Description LYST-interacting protein 5|SKD1-binding protein 1|Vps20-associated 1 homolog|dopamine-responsive gene 1 protein|homolog of mouse SKD1-binding protein 1|vacuolar protein sorting-associated protein VTA1 homolog
Swissprots Q9P0Q0 Q5TGM1 B4DW55 Q9H3K9 Q9NP79 Q6IAE8 Q9H0R2 E7ETQ7 E1P594
Accessions EAW47883 EAW47884 EAW47885 Q9NP79 AF060225 AAG43125 AF141341 AAG49444 AF151062 AAF36148 AF271994 AAF76210 AJ420507 AK000051 BAA90909 AK130738 AK301376 BAG62917 AL136684 CAB66619 AY007093 BC005937 AAH05937 BC006989 AAH06989 BC013217 BC022536 AAH22536 BM806661 CR457207 CAG33488 DA299959 DQ893520 ABM84446 DQ896504 ABM87503 NM_001286371 NP_001273300 NM_001286372 NP_001273301 NM_016485 NP_057569
Function Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding. {ECO:0000250, ECO:0000269|PubMed:15644320}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15644320}. Endosome membrane {ECO:0000305|PubMed:15644320}; Peripheral membrane protein {ECO:0000305|PubMed:15644320}.
Top Pathways Endocytosis

LIP5 CRISPR/Cas9 KO Plasmid (h) - sc-408230 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 HDR Plasmid (h) - sc-408230-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 Double Nickase Plasmid (h) - sc-408230-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 Double Nickase Plasmid (h2) - sc-408230-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 CRISPR Activation Plasmid (h) - sc-408230-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 CRISPR Activation Plasmid (h2) - sc-408230-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 Lentiviral Activation Particles (h) - sc-408230-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 Lentiviral Activation Particles (h2) - sc-408230-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIP5 siRNA (h) - sc-95648 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LIP5 shRNA Plasmid (h) - sc-95648-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LIP5 shRNA (h) Lentiviral Particles - sc-95648-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU083311 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22751 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22751 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11134 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11134

VTA1 siRNA (Human) - CRH9817 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VTA1 - MBS8235476 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human VTA1 (NM_016485.3) - SHH445332 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human VTA1(NM_016485.3) - SHL128970 from Creative biogene

Category siRNA
Species Reactivities Human

Human VTA1 siRNA - orb270319 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VTA1 shRNA Plasmid (Human) - CHH9817 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

VTA1 miRNA 3'UTR clone - MiUTR4H-TG09802 from Creative biogene

Species Reactivities Human
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