VTA1

Gene Symbol VTA1
Entrez Gene 51534
Alt Symbol C6orf55, DRG-1, DRG1, HSPC228, LIP5, My012, SBP1
Species Human
Gene Type protein-coding
Description vesicle (multivesicular body) trafficking 1
Other Description LYST-interacting protein 5|SKD1-binding protein 1|Vps20-associated 1 homolog|dopamine-responsive gene 1 protein|homolog of mouse SKD1-binding protein 1|vacuolar protein sorting-associated protein VTA1 homolog
Swissprots Q9P0Q0 Q5TGM1 B4DW55 Q9H3K9 Q9NP79 Q6IAE8 Q9H0R2 E7ETQ7 E1P594
Accessions EAW47883 EAW47884 EAW47885 Q9NP79 AF060225 AAG43125 AF141341 AAG49444 AF151062 AAF36148 AF271994 AAF76210 AJ420507 AK000051 BAA90909 AK130738 AK301376 BAG62917 AL136684 CAB66619 AY007093 BC005937 AAH05937 BC006989 AAH06989 BC013217 BC022536 AAH22536 BM806661 CR457207 CAG33488 DA299959 DQ893520 ABM84446 DQ896504 ABM87503 NM_001286371 NP_001273300 NM_001286372 NP_001273301 NM_016485 NP_057569
Function Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding. {ECO:0000250, ECO:0000269|PubMed:15644320}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15644320}. Endosome membrane {ECO:0000305|PubMed:15644320}; Peripheral membrane protein {ECO:0000305|PubMed:15644320}.
Top Pathways Endocytosis

LIP5 (C-1) - sc-374013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIP5 (C-1): sc-374013. Western blot analysis of LIP5 expression in HEK293 (A), Hep G2 (B) and K-562 (C) whole cell lysates.

LIP5 (D-19) - sc-168433 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LIP5 (H-300) - sc-134670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LIP5 (H-300): sc-134670. Western blot analysis of LIP5 expression in non-transfected 293T: sc-117752 (A), human LIP5 transfected 293T: sc-173648 (B) and Hep G2 (C) whole cell lysates.

LIP5 (D-6) - sc-374012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIP5 (D-6): sc-374012. Western blot analysis of LIP5 expression in HEK293 (A), Hep G2 (B) and K-562 (C) whole cell lysates.

LIP5 (T-16) - sc-168434 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIP5 (T-16): sc-168434. Western blot analysis of LIP5 expression in HeLa (A) and K-562 (B) whole cell lysates.

Anti-VTA1 Antibody (aa71-120) - LS-C107588 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
VTA1 antibody LS-C107588 Western blot of HepG2 cell lysate.

Anti-VTA1 Antibody (aa1-276) IHC-plus™ - LS-B10834 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-VTA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10834 concentration 7.5 ug/ml.

VTA1 Antibody - NBP1-32570 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: VTA1 Antibody [NBP1-32570] - Sample(30 ug whole cell lysate)A:H1299B:HeLa S3 C:MOLT4 12% SDS PAGE, antibody diluted at 1:1000.

VTA1 Antibody - NBP1-57637 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: VTA1 Antibody [NBP1-57637] - Titration: 0.2-1 ug/ml, Positive Control: HepG2 cell lysate.

VTA1 Antibody - NBP1-86745 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: VTA1 Antibody [NBP1-86745] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-630

Anti-VTA1 (21-35) antibody produced in rabbit - SAB1101442 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-VTA1 (21-35) : <B>Cat. No. SAB1101442</B>: Immunofluorescence of HUVEC cells using VTA1 (21-35) , Cat. No. SAB1101442 (red) at a 1:50 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-VTA1 antibody produced in rabbit - HPA030968 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-VTA1: <B>Cat. No. HPA030968</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.

Anti-VTA1, (N-terminal) antibody produced in rabbit - SAB2104792 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-VTA1, antibody produced in rabbit: <B>Cat. No. SAB2104792</B>: Immunoblotting analysis of VTA1 in HepG2 cell lysate with VTA1 anitbody at 1 μg/mL.

Anti-VTA1 (166-180) antibody produced in rabbit - SAB1101443 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-VTA1 (166-180) : <B>Cat. No. SAB1101443</B>: Immunofluorescence of HUVEC cells using VTA1 (166-180) , Cat. No. SAB1101443 (red) at a 1:50 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

VTA1 antibody - N-terminal region (ARP56921_P050) - ARP56921_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VTA1 antibody - 70R-21284 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

VTA1 Polyclonal Antibody - A4743 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

VTA1 antibody (OAGA00570) - OAGA00570 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VTA1 antibody - 70R-13075 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VTA1 Antibody - abx036222 from Abbexa

Host Rabbit
Clonality Polyclonal

VTA1 Antibody - abx003583 from Abbexa

Host Rabbit
Clonality Polyclonal

VTA1 antibody - 15786-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of Hela cells, using VTA1 antibody 15786-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

VTA1 antibody - H00051534-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

Rabbit Anti-Human VTA1 - 107-10678 from RayBiotech

Host Rabbit

VTA1 antibody - STJ26102 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
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