IYD

Gene Symbol	IYD
Entrez Gene	389434
Alt Symbol	C6orf71, DEHAL1, TDH4, dJ422F24.1
Species	Human
Gene Type	protein-coding
Description	iodotyrosine deiodinase
Other Description	IYD-1\|iodotyrosine dehalogenase 1
Swissprots	Q7Z7D7 C9JFW2 Q5F1L5 Q7Z7D8 Q5THM4 Q6ZP69 Q2VPW0 Q2VPW1 Q5F1L6 Q6PHW0
Accessions	EAW47769 Q6PHW0 AI823392 AK129950 BAC85255 AY259176 AAP22072 AY259177 AAP22073 AY424901 AAR84259 AY424902 AAR84260 AY957659 AAY41465 AY957660 AAY41466 AY957661 AAY41467 AY957662 AAY41468 BC056253 AAH56253 HQ447635 ADQ32120 XM_006715478 XP_006715541 XM_006715479 XP_006715542 XR_245516 NM_001164694 NP_001158166 NM_001164695 NP_001158167 NM_203395 NP_981932
Function	Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine. {ECO:0000269\|PubMed:15289438}.
Subcellular Location	Cell membrane {ECO:0000269\|PubMed:15289438}; Single-pass membrane protein {ECO:0000269\|PubMed:15289438}.
Tissue Specificity	Expressed at a high level in thyroid gland and at lower level in kidney and trachea. {ECO:0000269\|PubMed:15289438}.
Top Pathways	Thyroid hormone synthesis

DEHAL1 (D-18) - sc-242568 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-IYD antibody - ab118259 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-IYD antibody (ab118259) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : HEK293 cell lyste

Anti-IYD antibody - ab169434 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-IYD antibody (ab169434) at 1/500 dilutionLane 1 : IYD transfected lysateLane 2 : Non-transfected lysateLysates/proteins at 15 µl per lane.

Anti-IYD antibody - N-terminal - ab139657 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IYD antibody - N-terminal (ab139657) at 1 µg/ml + 293T whole cell lysate at 10 µg

Anti-IYD Antibody (aa22-71) - LS-C169818 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IYD Antibody (aa54-203) - LS-C178655 from LifeSpan Bioscience

Prices	$255.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

IYD Antibody - NBP2-31786 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: IYD Antibody [NBP2-31786] - Staining of human cell line CACO-2 shows localization to plasma membrane.

IYD Antibody - H00389434-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: IYD Antibody [H00389434-B01] - analysis of C6orf71 expression in transfected 293T cell line by C6orf71 MaxPab polyclonal antibody (B01). Lane 1: C6orf71 transfected lysate (33.40 KDa). Lane 2: Non-transfected lysate.

Anti-IYD antibody produced in rabbit - HPA059627 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-IYD: <B>Cat. No. HPA059627</B>: Immunohistochemical staining of Human thyroid gland shows strong cytoplasmic positivity in glandular cells.

IYD Antibody - N-terminal region (ARP66837_P050) - ARP66837_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

IYD antibody - orb78087 from Biorbyt

Prices	$425.00
Sizes	100 μg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed paraffin embedded fetal kidney showing membrane staining using IYD antibody

IYD antibody - 70R-18042 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

IYD Antibody - abx036965 from Abbexa

Host	Rabbit
Clonality	Polyclonal

Iodotyrosine dehalogenase 1 / IYD antibody - 16667-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Human liver tissue were subjected to SDS PAGE followed by western blot with 16667-1-AP(IYD antibody) at dilution of 1:1000

Iodotyrosine dehalogenase 1 / IYD antibody - H00389434-B01 from Acris Antibodies

Prices	$360.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot analysis of IYD expression in transfected 293T cell line (H00389434-T01) by IYD MaxPab polyclonal antibody.Lane 1: C6orf71 trans

IYD antibody - 16667-1-AP from Proteintech Group

Prices	$279.00
Sizes	con: 20 μg/150μl
Host	Rabbit
Clonality	Polyclonal

IYD, Polyclonal Antibody - MBS2521630 from MyBioSource

Prices	$195.00, $270.00, $435.00
Sizes	60 µl, 120 µl, 200 µl
Host	Rabbit
Clonality	Polyclonal

IYD, Polyclonal Antibody - MBS851512 from MyBioSource

Prices	$330.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

IYD, Polyclonal Antibody - MBS415548 from MyBioSource

Prices	$230.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

IYD Antibody - 39626 from Signalway Antibody

Prices	$390.00
Sizes	100 µl
Host	Rabbit

IYD Antibody - E305589 from Enogene

Prices	$275.00
Sizes	100ug/200ul

iodotyrosine deiodinase , Polyclonal Antibody - MBS711322 from MyBioSource

Prices	$230.00, $500.00
Sizes	50 µl, 150 µl
Host	Rabbit
Clonality	Polyclonal

IYD Antibody - EPP14506 from Elabscience

Prices	$296.00, $485.00
Sizes	120 μl, 200 μl
Host	Rabbit
Clonality	Polyclonal

Anti-IYD (aa 22-71) polyclonal antibody - DPABH-02027 from Creative Diagnostics

Host	Rabbit
Clonality	Polyclonal

Rabbit Anti-Human IYD Polyclonal antibody - DPABH-07839 from Creative Diagnostics

Host	Rabbit
Clonality	Polyclonal

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