IYD

Gene Symbol IYD
Entrez Gene 389434
Alt Symbol C6orf71, DEHAL1, TDH4, dJ422F24.1
Species Human
Gene Type protein-coding
Description iodotyrosine deiodinase
Other Description IYD-1|iodotyrosine dehalogenase 1
Swissprots Q7Z7D7 C9JFW2 Q5F1L5 Q7Z7D8 Q5THM4 Q6ZP69 Q2VPW0 Q2VPW1 Q5F1L6 Q6PHW0
Accessions EAW47769 Q6PHW0 AI823392 AK129950 BAC85255 AY259176 AAP22072 AY259177 AAP22073 AY424901 AAR84259 AY424902 AAR84260 AY957659 AAY41465 AY957660 AAY41466 AY957661 AAY41467 AY957662 AAY41468 BC056253 AAH56253 HQ447635 ADQ32120 XM_006715478 XP_006715541 XM_006715479 XP_006715542 XR_245516 NM_001164694 NP_001158166 NM_001164695 NP_001158167 NM_203395 NP_981932
Function Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine. {ECO:0000269|PubMed:15289438}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15289438}; Single-pass membrane protein {ECO:0000269|PubMed:15289438}.
Tissue Specificity Expressed at a high level in thyroid gland and at lower level in kidney and trachea. {ECO:0000269|PubMed:15289438}.
Top Pathways Thyroid hormone synthesis

DEHAL1 CRISPR/Cas9 KO Plasmid (h) - sc-408562 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 HDR Plasmid (h) - sc-408562-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 Double Nickase Plasmid (h) - sc-408562-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 Double Nickase Plasmid (h2) - sc-408562-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 CRISPR Activation Plasmid (h) - sc-408562-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 CRISPR Activation Plasmid (h2) - sc-408562-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 Lentiviral Activation Particles (h) - sc-408562-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 Lentiviral Activation Particles (h2) - sc-408562-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DEHAL1 siRNA (h) - sc-95564 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DEHAL1 shRNA Plasmid (h) - sc-95564-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DEHAL1 shRNA (h) Lentiviral Particles - sc-95564-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU145731 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10849 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10849 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IYD siRNA (Human) - CRJ7885 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IYD, siRNA - MBS8211617 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IYD (NM_203395.2) - SHH321823 from Creative biogene

Category siRNA
Species Reactivities Human

IYD shRNA Plasmid (Human) - CHJ7885 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more