IYD

Gene Symbol	IYD
Entrez Gene	389434
Alt Symbol	C6orf71, DEHAL1, TDH4, dJ422F24.1
Species	Human
Gene Type	protein-coding
Description	iodotyrosine deiodinase
Other Description	IYD-1|iodotyrosine dehalogenase 1
Swissprots	Q7Z7D7 C9JFW2 Q5F1L5 Q7Z7D8 Q5THM4 Q6ZP69 Q2VPW0 Q2VPW1 Q5F1L6 Q6PHW0
Accessions	EAW47769 Q6PHW0 AI823392 AK129950 BAC85255 AY259176 AAP22072 AY259177 AAP22073 AY424901 AAR84259 AY424902 AAR84260 AY957659 AAY41465 AY957660 AAY41466 AY957661 AAY41467 AY957662 AAY41468 BC056253 AAH56253 HQ447635 ADQ32120 XM_006715478 XP_006715541 XM_006715479 XP_006715542 XR_245516 NM_001164694 NP_001158166 NM_001164695 NP_001158167 NM_203395 NP_981932
Function	Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine. {ECO:0000269|PubMed:15289438}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:15289438}; Single-pass membrane protein {ECO:0000269|PubMed:15289438}.
Tissue Specificity	Expressed at a high level in thyroid gland and at lower level in kidney and trachea. {ECO:0000269|PubMed:15289438}.
Top Pathways	Thyroid hormone synthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IYD full length protein - ab132911 from Abcam Category Protein Source Wheat germ Species Human

Human IYD protein fragment - ab177648 from Abcam Category Protein Source E. coli Species Human

IYD protein (His-DHFR tag) - ab127839 from Abcam Category Protein Source E. coli Species Human

IYD Antibody Blocking Peptide - LS-E24241 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IYD Recombinant Protein - H00389434-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

IYD-Antibody-N-term-Blocking-Peptide - BP9837a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IYD protein (His tag) - 80R-3725 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Iodotyrosine dehalogenase 1 / IYD (24-214, His-tag) - AR51412PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Iodotyrosine dehalogenase 1 / IYD (24-214, His-tag) - AR51412PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Iodotyrosine dehalogenase 1 / IYD - H00389434-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Iodotyrosine dehalogenase 1 / IYD - H00389434-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Iodotyrosine dehalogenase 1 / IYD - H00389434-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

IYD, 24-214aa Human, His tag, E.coli - 01-P2592 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

IYD fusion protein - ag10146 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IYD fusion protein - Ag9939 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human IYD, His-tagged - IYD-5096H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human iodotyrosine deiodinase, His-tagged - IYD-495H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Iodotyrosine dehalogenase 1(IYD) - CSB-YP754272HU CSB-EP754272HU CSB-BP754272HU CSB-MP754272HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

IYD, 24-214aa, Human, His tag, E.coli (Denatured) - ATGP2592 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Iodotyrosine Deiodinase (Recombinant) - abx073431 from Abbexa

IYD Recombinant Protein Antigen - NBP2-31786PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IYD Peptide, Human - M34GP07842H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human IYD protein - orb259737 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Recombinant Human IYD Protein - NBP2-51606 from Novus Biologicals Category Protein Prices $259.00, $759.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Iodotyrosine Deiodinase, Human Recombinant - 228-20726-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Search more