PPBP

Gene Symbol	PPBP
Entrez Gene	5473
Alt Symbol	B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1
Species	Human
Gene Type	protein-coding
Description	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
Other Description	C-X-C motif chemokine 7|CXC chemokine ligand 7|beta-thromboglobulin|connective tissue-activating peptide III|leukocyte-derived growth factor|low-affinity platelet factor IV|macrophage-derived growth factor|neutrophil-activating peptide 2|neutrophil-activating peptide-2|platelet basic protein|small inducible cytokine B7|small inducible cytokine subfamily B, member 7|small-inducible cytokine B7|thrombocidin 1|thrombocidin 2|thromboglobulin, beta-1
Swissprots	P02775 Q6IBJ8 B2R5F3
Accessions	AAB46877 AAK29642 AAY41004 ADB85518 ADB85519 ADB85520 EAX05695 P02775 AK312166 BAG35100 BC028217 AAH28217 BQ447470 BX443846 CB112845 CR456805 CAG33086 DA419455 DQ891020 ABM81946 DQ894200 ABM85126 M54995 AAA62836 NM_002704 NP_002695
Function	LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. {ECO:0000269|PubMed:10877842, ECO:0000269|PubMed:7890771, ECO:0000269|PubMed:8950790, ECO:0000269|PubMed:9794434}.
Subcellular Location	Secreted.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CXCL7 Human ELISA Kit - ab100613 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 8.5 pg/ml Range 4.1 pg/ml - 1000 pg/ml

Human CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F2651 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 68.6-16667 pg/ml

Human CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F4967 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 51 pg/ml Range 68.6-16667 pg/ml

Mouse CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F4969 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.69 pg/ml Range 68.6-16667 pg/ml

Rat CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F4968 from LifeSpan Bioscience Category ELISA Kit Prices $520.00 Sizes 1 plate Sensitivity 1.45 pg/ml Range 68.6-16667 pg/ml

Rat CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F281 from LifeSpan Bioscience Category ELISA Kit Prices $620.00, $1,090.00, $2,380.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 68.6 pg/ml Range 68.6-16667 pg/ml

Human CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F963 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 68.6-16667 pg/ml

Mouse CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F510 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 10.97 pg/ml Range 68.6-16667 pg/ml

Human CXCL7 / PPBP ELISA Kit (Sandwich ELISA) - LS-F11253 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 15.6 Range 68.6-16667 pg/ml

Human NAP-2 / CXCL7 ELISA Kit - RAB0135 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human CXCL7/NAP-2 DuoSet ELISA - DY393 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Human NAP2 ELISA kit - 55R-2002 from Fitzgerald Category ELISA Kit Prices $435.00 Sizes 96 tests

NAP-2 ELISA Kit (Human) : 96 Wells (OKAG00053) - OKAG00053 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 16 pg/mL Range 16-2,000 pg/mL

Human CXCL7 ELISA Kit - orb178686 from Biorbyt Category ELISA Kit Prices $570.00 Sizes 96 well Sensitivity < 2 pg/ml Range 15.6 pg/ml-1000 pg/ml

Human Beta-Thromboglobulin ELISA Kit - abx150805 from Abbexa Category ELISA Kit Sensitivity 53 pg/ml Range 125 pg/ml - 8000 pg/ml

Human CTAPIII ELISA Kit - abx054637 from Abbexa Category ELISA Kit Sensitivity 4.5 ng/ml Range 12 ng/ml - 800 ng/ml

Human CXCL7 ELISA Kit - abx056130 from Abbexa Category ELISA Kit

Beta-Thromboglobulin (bTG), Human, ELISA Kit - SEA370Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 55pg/mL Range 125-8,000pg/mL

Beta-thromboglobulin, Beta-TG, Human, ELISA Kit - E0370h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 31.2-2000 pg/mL

Connective Tissue Activating Peptide III, CTAPIII, Human, ELISA Kit - E-EL-H0829 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000ng/mL

Neutrophil activating protein-2, NAP-2, Human, ELISA Kit - CSB-E04562h from ARP American Research Products Category ELISA Kit Prices $295.00, $395.00, $396.00, $397.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.11 ng/ml Range 0.45 ng/ml-30 ng/ml

Platelet basic protein, PPBP, Human, ELISA Kit - E0041h from ARP American Research Products Category ELISA Kit Prices $576.00 Sizes 96 t Range 15.6-1000 pg/mL

Transcobalamin II, Macrocytic Anemia (TCN2), Human, ELISA Kit - SEG796Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.061ng/mL Range 0.156-10ng/mL

Connective Tissue Activating Peptide III, CTAPIII, Rabbit, ELISA Kit - E-EL-RB0879 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Connective Tissue Activating Peptide III, CTAPIII, Chicken, ELISA Kit - E-EL-Ch1607 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

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