SRD5A2

Gene Symbol SRD5A2
Entrez Gene 6716
Alt Symbol -
Species Human
Gene Type protein-coding
Description steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Other Description 3-oxo-5-alpha-steroid 4-dehydrogenase 2|5 alpha-SR2|S5AR 2|SR type 2|steroid 5-alpha-reductase 2|type II 5-alpha reductase
Swissprots P31213 Q2M1R4 Q9BYE6 B2RE87
Accessions AAW56942 BAB40419 EAX00478 P31213 AK307235 AK316597 BAG38184 BC112252 AAI12253 BC113641 AAI13642 EF560740 ABQ59050 EU832809 ACE87820 GQ129244 ACT64378 HQ258121 ADR82875 M74047 AAA60586 XM_011533068 XP_011531370 XM_011533069 XP_011531371 XM_011533070 XP_011531372 XM_011533071 XP_011531373 XM_011533072 XP_011531374 NM_000348 NP_000339
Function Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Subcellular Location Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in high levels in the prostate and many other androgen-sensitive tissues.
Top Pathways Steroid hormone biosynthesis, Prostate cancer

5α-Reductase 2 CRISPR/Cas9 KO Plasmid (h) - sc-402353 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 HDR Plasmid (h) - sc-402353-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 Double Nickase Plasmid (h) - sc-402353-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 Double Nickase Plasmid (h2) - sc-402353-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 CRISPR Activation Plasmid (h) - sc-402353-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 CRISPR Activation Plasmid (h2) - sc-402353-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 Lentiviral Activation Particles (h) - sc-402353-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 Lentiviral Activation Particles (h2) - sc-402353-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

5α-Reductase 2 siRNA (h) - sc-41398 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

5α-Reductase 2 shRNA Plasmid (h) - sc-41398-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

5α-Reductase 2 shRNA (h) Lentiviral Particles - sc-41398-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SRD5A2 RNAi - H00006716-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU031361 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20561 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20561 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10016 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10016

SRD5A2 siRNA (Human) - CRH4585 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRD5A2 - MBS8237641 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SRD5A2(NM_000348.3) - SHL032150 from Creative biogene

Category siRNA
Species Reactivities Human

Human SRD5A2 siRNA - orb265087 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRD5A2 shRNA Plasmid (Human) - CHH4585 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SRD5A2 miRNA 3'UTR clone - MiUTR1H-09898 from Creative biogene

Species Reactivities Human
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