SRD5A2

Gene Symbol	SRD5A2
Entrez Gene	6716
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Other Description	3-oxo-5-alpha-steroid 4-dehydrogenase 2|5 alpha-SR2|S5AR 2|SR type 2|steroid 5-alpha-reductase 2|type II 5-alpha reductase
Swissprots	P31213 Q2M1R4 Q9BYE6 B2RE87
Accessions	AAW56942 BAB40419 EAX00478 P31213 AK307235 AK316597 BAG38184 BC112252 AAI12253 BC113641 AAI13642 EF560740 ABQ59050 EU832809 ACE87820 GQ129244 ACT64378 HQ258121 ADR82875 M74047 AAA60586 XM_011533068 XP_011531370 XM_011533069 XP_011531371 XM_011533070 XP_011531372 XM_011533071 XP_011531373 XM_011533072 XP_011531374 NM_000348 NP_000339
Function	Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Subcellular Location	Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in high levels in the prostate and many other androgen-sensitive tissues.
Top Pathways	Steroid hormone biosynthesis, Prostate cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SRD5A2 protein fragment - ab114946 from Abcam Category Protein Source Wheat germ Species Human

SRD5A2 peptide (2-13) - ab45681 from Abcam Category Peptide Species Human

SRD5A2 Antibody Blocking Peptide - LS-E25824 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SRD5A2 Antibody Blocking Peptide - LS-E16258 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SRD5A2 Antibody Blocking Peptide - LS-E16259 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SRD5A2 Antibody Blocking Peptide - LS-E7884 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SRD5A2 Antibody Blocking Peptide - LS-E27005 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SRD5A2 Protein - H00006716-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SRD5A2 Protein - H00006716-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

SRD5A2-Antibody-Center-Blocking-peptide - BP5552c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SRD5A2 blocking peptide - GTX47547-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Pig, Rat

SRD5A2 blocking peptide - GTX89611-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SRD5A2 Blocking Peptide - 33R-4423 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SRD5A2 Blocking Peptide - 33R-6350 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SRD5A2 Peptide - AC21-0656-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SRD5A2 Peptide - AC21-1830-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SRD5A2 - H00006716-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SRD5A2 - H00006716-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SRD5A2 Peptide - 46-432P from ProSci Category Peptide Species Human

SRD5A2 Peptide - 42-087P from ProSci Category Peptide Species Human

SRD5A2 fusion protein - ag18510 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SRD5A2 fusion protein - ag18200 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SRD5A2 - SRD5A2-31394TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human SRD5A2 - SRD5A2-836H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Steroid 5 Alpha Reductase 2 (SRD5a2) - RPM285Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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