CLIC2

Gene Symbol	CLIC2
Entrez Gene	1193
Alt Symbol	CLIC2b, MRXS32, XAP121
Species	Human
Gene Type	protein-coding
Description	chloride intracellular channel 2
Other Description	chloride intracellular channel protein 2
Swissprots	Q8TCE3 O15174 O15247 Q5JT80 A8K9S0
Accessions	CAA03948 CAI41464 CAO77905 EAW72624 EAW72625 O15247 AK292785 BAF85474 AM393055 CAL37933 AW961768 AY191592 AAO38670 BC005367 BC022305 AAH22305 BQ004708 BX482109 CD691162 DA901964 DQ892014 ABM82940 DQ895204 ABM86130 Y12696 CAA73228 NM_001289 NP_001280
Function	Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx. {ECO:0000269|PubMed:15147738, ECO:0000269|PubMed:15916532, ECO:0000269|PubMed:17945253}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15916532}. Membrane {ECO:0000305|PubMed:15916532}; Single-pass membrane protein {ECO:0000305|PubMed:15916532}. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Tissue Specificity	Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney. {ECO:0000269|PubMed:15147738, ECO:0000269|PubMed:22814392}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CLIC2 full length protein - ab106875 from Abcam Category Protein Source E. coli Species Human

Human CLIC2 full length protein - ab88002 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

CLIC2 Antibody Blocking Peptide - LS-E12480 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLIC2 Antibody Blocking Peptide - LS-E12481 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLIC2 Recombinant Protein - H00001193-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CLIC2 Protein - NBP1-51087 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CLIC2 Protein (OPPA00111) - OPPA00111 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human XAP121 protein - orb49296 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human CLIC2 protein - orb168127 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CLIC2 Blocking Peptide - 33R-3789 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CLIC2 Blocking Peptide - 33R-8293 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CLIC2 protein (His tag) - 80R-1777 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Human CLIC2 Protein - abx060027 from Abbexa Category Protein Source Yeast Species Human

CLIC2 (1-247, His-tag) - AR09960PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CLIC2 (1-247, His-tag) - AR09960PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CLIC2 - H00001193-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CLIC2 - H00001193-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Chloride Intracellular Channel 2, Human Recombinant - 228-12952-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Chloride Intracellular Channel 2 - 228-12952-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Chloride Intracellular Channel 2 - 228-12952-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

Chloride Intracellular Channel Protein 2, CLIC2, Human, Recombinant - 19-C266 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

CLIC2, 1-247aa, Human, His tag, E.coli - 01-1838-2 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

CLIC2 fusion protein - ag6766 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CLIC2 fusion protein - ag6764 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CLIC2 Human - PRPS-205 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

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