CLIC2

Gene Symbol CLIC2
Entrez Gene 1193
Alt Symbol CLIC2b, MRXS32, XAP121
Species Human
Gene Type protein-coding
Description chloride intracellular channel 2
Other Description chloride intracellular channel protein 2
Swissprots Q8TCE3 O15174 O15247 Q5JT80 A8K9S0
Accessions CAA03948 CAI41464 CAO77905 EAW72624 EAW72625 O15247 AK292785 BAF85474 AM393055 CAL37933 AW961768 AY191592 AAO38670 BC005367 BC022305 AAH22305 BQ004708 BX482109 CD691162 DA901964 DQ892014 ABM82940 DQ895204 ABM86130 Y12696 CAA73228 NM_001289 NP_001280
Function Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx. {ECO:0000269|PubMed:15147738, ECO:0000269|PubMed:15916532, ECO:0000269|PubMed:17945253}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15916532}. Membrane {ECO:0000305|PubMed:15916532}; Single-pass membrane protein {ECO:0000305|PubMed:15916532}. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Tissue Specificity Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney. {ECO:0000269|PubMed:15147738, ECO:0000269|PubMed:22814392}.

CLIC2 CRISPR/Cas9 KO Plasmid (h) - sc-409129 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 HDR Plasmid (h) - sc-409129-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 Double Nickase Plasmid (h) - sc-409129-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 Double Nickase Plasmid (h2) - sc-409129-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 CRISPR Activation Plasmid (h) - sc-409129-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 CRISPR Activation Plasmid (h2) - sc-409129-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 Lentiviral Activation Particles (h) - sc-409129-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 Lentiviral Activation Particles (h2) - sc-409129-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC2 siRNA (h) - sc-60402 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLIC2 shRNA Plasmid (h) - sc-60402-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLIC2 shRNA (h) Lentiviral Particles - sc-60402-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU091651 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6229 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6229 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLIC2 siRNA (Human) - CRH0853 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLIC2 RNAi - H00001193-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CLIC2 - MBS8240696 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLIC2 (NM_001289.4) - SHH265289 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CLIC2(NM_001289.4) - SHG182527 from Creative biogene

Category siRNA
Species Reactivities Human

Human CLIC2 siRNA - orb261355 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLIC2 shRNA Plasmid (Human) - CHH0853 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLIC2 miRNA 3'UTR clone - MiUTR1H-02221 from Creative biogene

Species Reactivities Human
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