CLIC2

Gene Symbol	CLIC2
Entrez Gene	1193
Alt Symbol	CLIC2b, MRXS32, XAP121
Species	Human
Gene Type	protein-coding
Description	chloride intracellular channel 2
Other Description	chloride intracellular channel protein 2
Swissprots	Q8TCE3 O15174 O15247 Q5JT80 A8K9S0
Accessions	CAA03948 CAI41464 CAO77905 EAW72624 EAW72625 O15247 AK292785 BAF85474 AM393055 CAL37933 AW961768 AY191592 AAO38670 BC005367 BC022305 AAH22305 BQ004708 BX482109 CD691162 DA901964 DQ892014 ABM82940 DQ895204 ABM86130 Y12696 CAA73228 NM_001289 NP_001280
Function	Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx. {ECO:0000269\|PubMed:15147738, ECO:0000269\|PubMed:15916532, ECO:0000269\|PubMed:17945253}.
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:15916532}. Membrane {ECO:0000305\|PubMed:15916532}; Single-pass membrane protein {ECO:0000305\|PubMed:15916532}. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Tissue Specificity	Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney. {ECO:0000269\|PubMed:15147738, ECO:0000269\|PubMed:22814392}.

CLIC2 (C-13) - sc-50905 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CLIC2 (C-13): sc-50905. Western blot analysis of CLIC2 expression in non-transfected: sc-117752 (A) and CLIC2 transfected (B) 293T whole cell lysates.

CLIC2 (L-13) - sc-50907 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CLIC2 (L-13): sc-50907. Western blot analysis of CLIC2 expression in non-transfected: sc-117752 (A) and CLIC2 transfected (B) 293T whole cell lysates.

CLIC2 (T-13) - sc-50908 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CLIC2 (T-13): sc-50908. Western blot analysis of CLIC2 expression in non-transfected: sc-117752 (A) and CLIC2 transfected (B) 293T whole cell lysates.

Anti-CLIC2 antibody - ab28687 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CLIC2 antibody (ab28687) at 1.25 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µg/mlSecondaryHRP conjugated anti-Rabbit IgG

Anti-CLIC2 antibody - ab89916 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-CLIC2 antibody (ab89916) at 1 µg/ml + Human spleen tissue lysate at 50 µg

Anti-CLIC2 antibody [EPR6494] - ab175230 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6494

All lanes : Anti-CLIC2 antibody [EPR6494] (ab175230) at 1/1000 dilutionLane 1 : Human fetal liver lysateLane 2 : Human heart lysateLane 3 : Human testis lysateLysates/proteins at 10 µg per lane.

Anti-CLIC2 antibody [EPR6495] - ab126727 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6495

All lanes : Anti-CLIC2 antibody [EPR6495] (ab126727) at 1/1000 dilutionLane 1 : Human fetal liver lysateLane 2 : Human heart lysateLane 3 : Human testis lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CLIC2 Antibody (aa1-247) - LS-C128128 from LifeSpan Bioscience

Prices	$445.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-CLIC2 Antibody (aa162-211) - LS-C30656 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CLIC2 Antibody (aa101-150) - LS-C30657 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CLIC2 Antibody (N-Terminus) - LS-C345776 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of CLIC2 Antibody with human Fetal Liver lysate.

Anti-CLIC2 Antibody (Internal, clone EPR6495) - LS-C152271 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6495

Western blot analysis on (A) fetal liver, (B) human heart, and (C) human testis lysates using anti-CLIC2 antibody.

Anti-CLIC2 Antibody (clone 2C1) - LS-C196934 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2C1

Western Blot analysis of CLIC2 expression in transfected 293T cell line by CLIC2 monoclonal antibody (M01), clone 2C1.Lane 1: CLIC2 transfected lysate (Predicted MW: 28.4 KDa).Lane 2: Non-transfected lysate.

CLIC2 Antibody - NBP2-32516 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: CLIC2 Antibody [NBP2-32516] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

CLIC2 Antibody - NBP1-80059 from Novus Biologicals

Prices	$139.00, $299.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

CLIC2 Antibody - NBP1-80058 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: CLIC2 Antibody [NBP1-80058] - HepG2 cell lysate, concentration 1.25ug/ml.

CLIC2 Antibody - H00001193-B02P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

CLIC2 Antibody - H00001193-B02 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: CLIC2 Antibody [H00001193-B02] - Western Blot analysis of CLIC2 expression in human spleen.

CLIC2 Antibody - H00001193-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: CLIC2 Antibody [H00001193-B01] - analysis of CLIC2 expression in transfected 293T cell line by CLIC2 MaxPab polyclonal antibody (B01). Lane 1: CLIC2 transfected lysate (27.28 KDa). Lane 2: Non-transfected lysate.

CLIC2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13629R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CLIC2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13629R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CLIC2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13629R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CLIC2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13629R-A647 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CLIC2 Polyclonal Antibody, Cy3 Conjugated - bs-13629R-Cy3 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CLIC2 Polyclonal Antibody, Cy5 Conjugated - bs-13629R-Cy5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Search more