TNR

Gene Symbol TNR
Entrez Gene 7143
Alt Symbol TN-R
Species Human
Gene Type protein-coding
Description tenascin R
Other Description janusin|restrictin|tenascin-R
Swissprots Q15568 C9J563 Q5R3G0 Q92752
Accessions EAW90994 EAW90995 Q92752 AK295823 BAG58640 AV650210 BC129830 AAI29831 DA804585 DB068074 X98085 CAA66709 Y13359 Z67996 CAA91947 XM_011509947 XP_011508249 XM_011509948 XP_011508250 XM_011509949 XP_011508251 NM_003285 NP_003276
Function Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adh
Subcellular Location Secreted, extracellular space, extracellular matrix.
Tissue Specificity Brain specific. {ECO:0000269|PubMed:8626505}.
Top Pathways Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, MicroRNAs in cancer

Tenascin-R (A-2) - sc-376341 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Tenascin-R (A-2): sc-376341. Western blot analysis of Tenascin-R expression in rat brain tissue extract.

Tenascin-R (E-18) - sc-9875 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Tenascin-R (E-18): sc-9875. Western blot analysis of Tenascin-R expression in T98G (A) and U-87 MG (B) whole cell lysates.

Tenascin-R (N-20) - sc-9874 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Tenascin-R (H-60) - sc-25718 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Tenascin-R (H-60): sc-25718. Immunofluorescence staining of normal mouse skin frozen section showing extracellular staining.

Tenascin-R (9) - sc-136098 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal
Tenascin-R (9): sc-136098. Western blot analysis of Tenascin-R expression in rat cerebrum tissue extract.

Anti-TNR antibody - ab198863 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue labeling TNR with ab198863 at 1/60 dilution.

Anti-TNR antibody - ab121916 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121916, at 1/600 dilution, staining TNR in paraffin embedded Human hippocampus tissue by Immunohistochemistry.

Anti-TNR antibody - ab121921 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121921 at 1/50 dilution staining TNR in paraffin-embedded Human rectum tissue by Immunohistochemistry.

Anti-TNR antibody - ab155034 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TNR antibody (ab155034) at 1/500 dilution + Mouse brain whole cell lysate at 50 µg

Anti-TNR antibody - ab122088 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab122088, at 1/50 dilution, staining TNR in paraffin-embedded Human Cerebral cortex tissue by Immunohistochemistry.

Anti-TNR / Tenascin R Antibody - LS-C38814 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TNR / Tenascin R Antibody (clone 1D12) - LS-C198357 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D12
Detection limit for recombinant GST tagged TNR is 0.3 ng/ml as a capture antibody.

Anti-TNR / Tenascin R Antibody (C-Terminus) - LS-C312845 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
TNR / Tenascin R antibody. IHC(P): Rat Brain Tissue.

Tenascin R Antibody - AF3865 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Tenascin R was detected in immersion fixed paraffin-embedded sections of human brainstem (medulla) using 1.7 µg/mL Goat Anti-Human Tenascin R Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3865) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Tenascin R Antibody - NBP1-86399 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: TNR Antibody [NBP1-86399] - Staining of human hippocampus shows distinct positivity in the neuropil.

Tenascin R Antibody - NBP1-86398 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: TNR Antibody [NBP1-86398] - Staining of human rectum shows strong cytoplasmic positivity in neuroendocrine cells.

Tenascin R Antibody - NBP1-86350 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Tenascin R Antibody [NBP1-86350] - Staining of human cerebral cortex shows distinct positivity in neuropil.

Tenascin R Antibody - NBP2-20677 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Tenascin R Antibody - H00007143-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Tenascin R Antibody (1D12) - H00007143-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D12
Sandwich ELISA: Tenascin R Antibody (1D12) [H00007143-M01] - Detection limit for recombinant GST tagged TNR is 0.3 ng/ml as a capture antibody.

TNR/Tenascin R/TENR Polyclonal Antibody - bs-11068R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TNR/Tenascin R/TENR Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11068R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TNR/Tenascin R/TENR Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11068R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TNR/Tenascin R/TENR Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11068R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TNR/Tenascin R/TENR Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11068R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more