TNR

Gene Symbol	TNR
Entrez Gene	7143
Alt Symbol	TN-R
Species	Human
Gene Type	protein-coding
Description	tenascin R
Other Description	janusin|restrictin|tenascin-R
Swissprots	Q15568 C9J563 Q5R3G0 Q92752
Accessions	EAW90994 EAW90995 Q92752 AK295823 BAG58640 AV650210 BC129830 AAI29831 DA804585 DB068074 X98085 CAA66709 Y13359 Z67996 CAA91947 XM_011509947 XP_011508249 XM_011509948 XP_011508250 XM_011509949 XP_011508251 NM_003285 NP_003276
Function	Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adh
Subcellular Location	Secreted, extracellular space, extracellular matrix.
Tissue Specificity	Brain specific. {ECO:0000269|PubMed:8626505}.
Top Pathways	Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Tenascin R, Human, ELISA Kit - E01T0258 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL,

Tenascin-R, TN-R, Human, ELISA Kit - CSB-E09329h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Tenascin-R, TNR, Human, ELISA Kit - E1328h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Tenascin R, TNR, Human, ELISA Kit - E-EL-H1424 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Tenascin R, TNR, Rabbit, ELISA Kit - E-EL-RB1946 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Tenascin R, TNR, Chicken, ELISA Kit - E-EL-Ch1960 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Tenascin R, TNR, Porcine, ELISA Kit - E-EL-P0988 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Tenascin R, TNR, Guinea Pig, ELISA Kit - E-EL-GP0346 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Tenascin R, TNR, Monkey, ELISA Kit - E-EL-MK0146 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human TN-R ELISA Kit - HT0535 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human TNR ELISA Kit - HT0265 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine TNR ELISA Kit - AT0265 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine TN-R ELISA Kit - AT0535 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

TNR, ELISA Kit - MBS2512133 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TNR, ELISA Kit - MBS2512035 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TNR, ELISA Kit - MBS2512300 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

TNR, ELISA Kit - MBS2500804 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

TNR, ELISA Kit - MBS2511860 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TNR, ELISA Kit - MBS2514429 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human TNR(Tenascin R) ELISA Kit - E-EL-H1424 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Tenascin R, ELISA Kit - MBS723974 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tenascin R, ELISA Kit - MBS734227 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Tenascin R, ELISA Kit - MBS080917 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tenascin R, ELISA Kit - MBS105498 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tenascin R, ELISA Kit - MBS016667 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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