RNF6

Gene Symbol	RNF6
Entrez Gene	6049
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ring finger protein (C3H2C3 type) 6
Other Description	E3 ubiquitin-protein ligase RNF6\|RING-H2 protein RNF-6
Swissprots	Q9BZP5 Q5W0H0 B4DDP0 Q9UF41 Q9Y252
Accessions	EAX08380 EAX08381 EAX08382 EAX08383 Q9Y252 AF293342 AAK00848 AJ010346 CAB40413 AJ010347 CAB40414 AK293272 BAG56801 AK312435 BAG35344 AL133621 CAB63747 AY009109 AAG49400 BC034688 AAH34688 BI461269 BP310130 BU633523 CR749238 CAH18094 DB062601 DC310579 DQ891481 ABM82407 DQ896825 ABM87824 XM_005266485 XP_005266542 XM_005266486 XP_005266543 XM_006719854 XP_006719917 XM_011535177 XP_011533479 XM_011535178 XP_011533480 NM_005977 NP_005968 NM_183043 NP_898864 NM_183044 NP_898865 NM_183045
Function	E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator. {ECO:0000269\|PubMed:19345326}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:19345326}. Cytoplasm {ECO:0000269\|PubMed:19345326}. Cell projection, axon {ECO:0000250}. Nucleus, PML body {ECO:0000250}. Note=Localizes to the PML nuclear bodies in Sertoli cells. {ECO:0000250}.
Tissue Specificity	Weakly expressed in peripheral blood, spleen, prostate, testis and ovary. According to PubMed:18368307, it is preferentially expressed in testis and ovary and hardly detected in other tissues. {ECO:0000269\|PubMed:18368307, ECO:0000269\|PubMed:19345326}.

RNF6 (H-143) - sc-367587 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

RNF6 (I-14) - sc-133353 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-RNF6 antibody - ab80427 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 antibody (ab80427) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RNF6 antibody - ab58293 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Western blot against tagged recombinant protein immunogen using ab58293 RNF6 antibody at 1ug/ml.

Anti-RNF6 antibody - ab76773 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-RNF6 antibody (ab76773) at 1/500 dilutionLane 1 : RNF6 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-RNF6 antibody - C-terminal - ab154927 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 antibody - C-terminal (ab154927) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-RNF6 antibody - C-terminal - ab138968 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 antibody - C-terminal (ab138968) at 1/100 dilution + A549 cell line lysate at 35 µg

Anti-RNF6 antibody - N-terminal - ab166673 from Abcam

Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-RNF6 antibody - N-terminal (ab166673) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extract

Anti-RNF6 Antibody (aa529-558, AP) - LS-C240152 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (aa529-558, APC) - LS-C240153 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (aa529-558, Biotin) - LS-C240154 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (aa529-558, PE) - LS-C240156 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (aa529-558, FITC) - LS-C240155 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (aa529-558, Azide-free, HRP) - LS-C248032 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (aa528-558) - LS-C324750 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody - LS-C332492 from LifeSpan Bioscience

Prices	$305.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (aa72-121) - LS-C110749 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

RNF6 antibody LS-C110749 Western blot of Fetal Spleen lysate.

Anti-RNF6 Antibody (aa578-627) - LS-C80542 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RNF6 Antibody (aa529-558) - LS-C158879 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

RNF6 Antibody western blot of A549 cell line lysates (35 ug/lane). The RNF6 antibody detected the RNF6 protein (arrow).

Anti-RNF6 Antibody (N-Terminus) - LS-C31369 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-RNF6 Antibody (clone 3B1) - LS-C198095 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3B1

Immunofluorescence of monoclonal antibody to RNF6 on HeLa cell . [antibody concentration 10 ug/ml]

RNF6 Antibody - NBP2-38445 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: RNF6 Antibody [NBP2-38445] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative Control. Lane 3: Overexpression lysate

RNF6 Antibody - NBP1-31039 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

RNF6 Antibody (3B1) - H00006049-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	3B1

RNF6 Antibody - H00006049-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: RNF6 Antibody [H00006049-B01P] - Analysis of RNF6 expression in HeLa.

Search more