Gene Symbol | MAGEA6 |
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Entrez Gene | 4105 |
Alt Symbol | CT1.6, MAGE-3b, MAGE3B, MAGE6 |
Species | Human |
Gene Type | protein-coding |
Description | melanoma antigen family A6 |
Other Description | MAGE-6 antigen|MAGE3B antigen|cancer/testis antigen 1.6|cancer/testis antigen family 1, member 6|melanoma antigen family A, 6|melanoma-associated antigen 6 |
Swissprots | P43360 A8IF93 Q6NW44 |
Accessions | AAA68875 P43360 AK289437 BAF82126 BC041599 AAH41599 BC067731 AAH67731 BM843807 BX640600 CAE45706 D32076 BAA06842 EU161101 ABW06860 U10339 AAA19006 XM_011531162 XP_011529464 NM_005363 NP_005354 NM_175868 NP_787064 |
Function | Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. {ECO:0000269|PubMed:17942928, ECO:0000269|PubMed:20864041}. |
Tissue Specificity | Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. |
Human MAGEA6 full length protein - ab116736 from Abcam
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Human MAGEA6 full length protein - ab126656 from Abcam
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Human MAGEA6 full length protein - ab190384 from Abcam
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MAGEA6-Antibody-C-term-Blocking-Peptide - BP6168a from Abgent, a WuXi AppTec company
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MAGEA6 protein (His tag) - 80R-2301 from Fitzgerald
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MAGE-6 (1-314, His-tag) - AR50385PU-N from Acris Antibodies
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MAGE-6 (1-314, His-tag) - AR50385PU-S from Acris Antibodies
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MAGE-6 - H00004105-P01-10 from Acris Antibodies
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MAGE-6 - H00004105-P01-25 from Acris Antibodies
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MAGEA6, 1-314aa, Human, His tag, E.coli - 01-P1561 from ARP American Research Products
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MAGEA6 fusion protein - ag6148 from Proteintech Group
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MAGEA6 Human - PRPS-1120 from NeoScientific
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Recombinant Human MAGEA6 - MAGEA6-30166TH from Creative Biomart
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Recombinant Human Melanoma Antigen Family A, 6, His-tagged - MAGEA6-6788H from Creative Biomart
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Recombinant Human MAGEA6 - MAGEA6-403H from Creative Biomart
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MAGEA6 Blocking Peptide - CBP1715 from Cohesion Biosciences
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MAGEA6 Peptide - BS60272P from Bioworld Technology
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Recombinant Human Melanoma-associated antigen 6(MAGEA6) - CSB-YP013332HU CSB-EP013332HU CSB-BP013332HU CSB-MP013332HU from Cusabio
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MAGEA6, 1-314aa, Human, His tag, E.coli - ATGP1561 from ATGen
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MAGEA6 Protein - abx163096 from Abbexa
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Melanoma Antigen Family A, 6 Protein (Recombinant) - abx263281 from Abbexa
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MAGE-6 (290-298) - ta-474 from Creative Peptides
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MAGE-6 (168-176) - ta-475 from Creative Peptides
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MAGE-6 (293-301) - ta-476 from Creative Peptides
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MAGE-6 (121-134) - ta-477 from Creative Peptides
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