Gene Symbol | MAGEA6 |
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Entrez Gene | 4105 |
Alt Symbol | CT1.6, MAGE-3b, MAGE3B, MAGE6 |
Species | Human |
Gene Type | protein-coding |
Description | melanoma antigen family A6 |
Other Description | MAGE-6 antigen|MAGE3B antigen|cancer/testis antigen 1.6|cancer/testis antigen family 1, member 6|melanoma antigen family A, 6|melanoma-associated antigen 6 |
Swissprots | P43360 A8IF93 Q6NW44 |
Accessions | AAA68875 P43360 AK289437 BAF82126 BC041599 AAH41599 BC067731 AAH67731 BM843807 BX640600 CAE45706 D32076 BAA06842 EU161101 ABW06860 U10339 AAA19006 XM_011531162 XP_011529464 NM_005363 NP_005354 NM_175868 NP_787064 |
Function | Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. {ECO:0000269|PubMed:17942928, ECO:0000269|PubMed:20864041}. |
Tissue Specificity | Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. |
Anti-MAGEA6 antibody - ab38495 from Abcam
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Anti-MAGEA6 antibody - ab115677 from Abcam
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Anti-MAGEA6 Antibody (C-Terminus, AP) - LS-C279080 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (C-Terminus, APC) - LS-C279081 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (C-Terminus, FITC) - LS-C279082 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (C-Terminus, PE) - LS-C279085 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (C-Terminus, Biotin) - LS-C279083 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (C-Terminus, Azide-free, HRP) - LS-C279084 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody - LS-C314008 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (C-Terminus) - LS-C327799 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (aa216-265) - LS-C111082 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (aa214-243) - LS-C99937 from LifeSpan Bioscience
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Anti-MAGEA6 Antibody (aa229-243) IHC-plus⢠- LS-B886 from LifeSpan Bioscience
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MAGEA6 Antibody - NBP1-56603 from Novus Biologicals
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MAGEA6 Antibody - NBP1-02552 from Novus Biologicals
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Anti-MAGEA6 antibody produced in rabbit - SAB2101420 from Sigma-Aldrich
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Anti-MAGEA6 (C-term) antibody produced in rabbit - SAB1300320 from Sigma-Aldrich
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MAGEA6 antibody - middle region (ARP46125_P050) - ARP46125_P050 from Aviva Systems Biology
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MAGEA6-Antibody-C-term - AP6168a from Abgent, a WuXi AppTec company
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MAGEA6 antibody - GTX85853 from GeneTex
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MAGEA6 antibody, Internal - GTX46483 from GeneTex
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MAGEA6 Antibody - C-terminal region (OAAB16516) - OAAB16516 from Aviva Systems Biology
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MAGEA6 antibody - 70R-3558 from Fitzgerald
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Anti -MAGEA6 (Melanoma-Associated Antigen 6, Cancer/Testis Antigen 1.6, CT1.6, MAGE-6Antigen, MAGE3B Antigen, MAGE6, MAGE-A6) - 223992 from USBiological Life Science
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Melanoma Antigen Family A, 6 Antibody - abx113660 from Abbexa
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