Gene Symbol | CDC26 |
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Entrez Gene | 246184 |
Alt Symbol | ANAPC12, APC12, C9orf17 |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle 26 |
Other Description | CDC26 subunit of anaphase promoting complex|anaphase-promoting complex subunit 12|anaphase-promoting complex subunit CDC26|cell division cycle 26 homolog|cell division cycle protein 26 homolog |
Swissprots | Q8NHZ8 |
Accessions | EAW87360 EAW87361 Q8NHZ8 AF503918 AAM34207 BC042534 AAH42534 BC066300 AAH66300 BF244254 BQ446788 CA446805 CD685602 HQ448488 ADQ32968 NM_139286 NP_644815 |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. {ECO:0000269|PubMed:18485873}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection |
Cdc26 (E-14) - sc-107476 from Santa Cruz Biotechnology
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Cdc26 (FL-85) - sc-135227 from Santa Cruz Biotechnology
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Cdc26 (S-14) - sc-107478 from Santa Cruz Biotechnology
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Anti-CDC26 Antibody (aa1-85) - LS-C186183 from LifeSpan Bioscience
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Anti-CDC26 Antibody (C-Terminus) - LS-C116822 from LifeSpan Bioscience
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Anti-CDC26 Antibody (aa21-70) - LS-C116823 from LifeSpan Bioscience
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CDC26 Antibody - NBP1-91771 from Novus Biologicals
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CDC26 Antibody - NBP1-33112 from Novus Biologicals
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Anti-CDC26 antibody produced in rabbit - SAB2107368 from Sigma-Aldrich
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Anti-CDC26 antibody produced in rabbit - HPA044130 from Sigma-Aldrich
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Anti-CDC26 (1-15) antibody produced in rabbit - SAB1103974 from Sigma-Aldrich
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Anti-CDC26 antibody produced in rabbit - SAB2107369 from Sigma-Aldrich
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Anti-CDC26 (56-70) antibody produced in rabbit - SAB1103975 from Sigma-Aldrich
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CDC26 antibody - C-terminal region (ARP59256_P050) - ARP59256_P050 from Aviva Systems Biology
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CDC26 antibody - middle region (ARP59257_P050) - ARP59257_P050 from Aviva Systems Biology
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CDC26 antibody [N1C3] - GTX111007 from GeneTex
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CDC26 antibody - orb69875 from Biorbyt
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CDC26 antibody - 70R-9717 from Fitzgerald
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CDC26 antibody (OAGA00877) - OAGA00877 from Aviva Systems Biology
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CDC26 antibody - 70R-13395 from Fitzgerald
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CDC26 antibody - 70R-9718 from Fitzgerald
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CDC26 antibody - 14125-1-AP from Acris Antibodies
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Rabbit Anti-Human CDC26 - 107-10943 from RayBiotech
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CDC26 antibody - 14125-1-AP from Proteintech Group
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CDC26 antibody - 22216 from Signalway Antibody
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