Gene Symbol | CDC26 |
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Entrez Gene | 246184 |
Alt Symbol | ANAPC12, APC12, C9orf17 |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle 26 |
Other Description | CDC26 subunit of anaphase promoting complex|anaphase-promoting complex subunit 12|anaphase-promoting complex subunit CDC26|cell division cycle 26 homolog|cell division cycle protein 26 homolog |
Swissprots | Q8NHZ8 |
Accessions | EAW87360 EAW87361 Q8NHZ8 AF503918 AAM34207 BC042534 AAH42534 BC066300 AAH66300 BF244254 BQ446788 CA446805 CD685602 HQ448488 ADQ32968 NM_139286 NP_644815 |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. {ECO:0000269|PubMed:18485873}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection |
Human Cdc26 / Apc12 full length protein - ab108123 from Abcam
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CDC26 Antibody Blocking Peptide - LS-E21672 from LifeSpan Bioscience
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CDC26 Antibody Blocking Peptide - LS-E21673 from LifeSpan Bioscience
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Recombinant Human CDC26 Protein - NBP1-72341 from Novus Biologicals
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CDC26 Recombinant Protein - P3442 from Novus Biologicals
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CDC26-Antibody-C-term-Blocking-peptide - BP5544b from Abgent, a WuXi AppTec company
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CDC26 Protein - GTX111007-pro from GeneTex
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CDC26 Protein (OPPA00133) - OPPA00133 from Aviva Systems Biology
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Human CDC26 protein - orb168085 from Biorbyt
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CDC26 protein (His tag) - 80R-1851 from Fitzgerald
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CDC26 (1-85, His-tag) - AR39035PU-L from Acris Antibodies
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CDC26 (1-85, His-tag) - AR39035PU-N from Acris Antibodies
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CDC26 - P3442 from Acris Antibodies
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Cell Division Cycle 26, Human Recombinant - 228-12995-1 from RayBiotech
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Recombinant Human Cell Division Cycle 26 - 228-12995-2 from RayBiotech
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Recombinant Human Cell Division Cycle 26 - 228-12995-3 from RayBiotech
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CDC26, 1-85aa, Human, His tag, E.coli - 01-CDC-26HT from ARP American Research Products
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CDC26 fusion protein - ag5387 from Proteintech Group
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CDC26 fusion protein - Ag5276 from Proteintech Group
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CDC26 Human - PRPS-248 from NeoScientific
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Recombinant Human Cell Division Cycle 26 Protein - BP001871-PRO-241 from Syd Labs
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CDC26, 1-85aa, Recombinant Protein - GWB-P0943G from Genway Biotech
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Recombinant Human Cell Division Cycle 26 Homolog (S. cerevisiae), His-tagged - CDC26-1678H from Creative Biomart
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Recombinant Human CDC26, His-tagged - CDC26-27901TH from Creative Biomart
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Recombinant Human CDC26, His-tagged - CDC26-3554H from Creative Biomart
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