RFX3

Gene Symbol	RFX3
Entrez Gene	5991
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	regulatory factor X, 3 (influences HLA class II expression)
Other Description	DNA binding protein RFX3|transcription factor RFX3
Swissprots	Q95HL5 D3DRH9 Q5JTL7 Q6NW13 Q95HL6 D3DRH8 Q5JTL8 Q8WTU4 P48380 A8K0H5
Accessions	EAW58794 EAW58795 EAW58796 EAW58797 EAW58798 EAW58799 P48380 AI811824 AK127804 AK289540 BAF82229 AK310956 AW152407 BC022191 AAH22191 BC067778 AAH67778 BM666287 BU170404 DB036180 DB461398 X76092 CAA53706 XM_006716840 XP_006716903 XM_006716842 XP_006716905 XM_006716843 XP_006716906 XM_006716844 XP_006716907 XM_006716845 XP_006716908 XM_006716847 XP_006716910 XM_011517998 XP_011516300 XM_011517999 XP_011516301 XM_011518000 XP_011516302 XM_011518001 XP_011516303 NM_001282116 NP_001269045 NM_001282117 NP_001269046 NM_002919 NP_002910 NM_134428 NP_602304
Function	Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left- right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5) (By similarity). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes. Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal c
Subcellular Location	Nucleus {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RFX3-Over-expression-Lysate - LY15129a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

RFX3 293T Cell Transient Overexpression Lysate(Denatured) - H00005991-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

RFX3 overexpression lysate - LY403344 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

RFX3 293 Cell Lysate - 402901 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

RFX3 Overexpression Lysate (Denatured) - H00005991-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

RFX3 Overexpression Lysate (Native) - NBL1-15306 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

RFX3 Over-expression Lysate Product - GWB-1B0D1D from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human RFX3 Knockdown Stable Cell Line - CSC-DC013206 from Creative biogene Category Cell Line Species Human

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