RFX3

Gene Symbol	RFX3
Entrez Gene	5991
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	regulatory factor X, 3 (influences HLA class II expression)
Other Description	DNA binding protein RFX3|transcription factor RFX3
Swissprots	Q95HL5 D3DRH9 Q5JTL7 Q6NW13 Q95HL6 D3DRH8 Q5JTL8 Q8WTU4 P48380 A8K0H5
Accessions	EAW58794 EAW58795 EAW58796 EAW58797 EAW58798 EAW58799 P48380 AI811824 AK127804 AK289540 BAF82229 AK310956 AW152407 BC022191 AAH22191 BC067778 AAH67778 BM666287 BU170404 DB036180 DB461398 X76092 CAA53706 XM_006716840 XP_006716903 XM_006716842 XP_006716905 XM_006716843 XP_006716906 XM_006716844 XP_006716907 XM_006716845 XP_006716908 XM_006716847 XP_006716910 XM_011517998 XP_011516300 XM_011517999 XP_011516301 XM_011518000 XP_011516302 XM_011518001 XP_011516303 NM_001282116 NP_001269045 NM_001282117 NP_001269046 NM_002919 NP_002910 NM_134428 NP_602304
Function	Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left- right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5) (By similarity). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes. Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal c
Subcellular Location	Nucleus {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RFX3 full length protein - ab159335 from Abcam Category Protein Source Wheat germ Species Human

RFX3 Antibody Blocking Peptide - LS-E1817 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RFX3 Protein - H00005991-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RFX3-Antibody-C-term-Blocking-peptide - BP12626b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RFX3 Blocking Peptide - abx063202 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

RFX3 - H00005991-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RFX3 - H00005991-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RFX3 fusion protein - Ag6413 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human RFX3, His-tagged - RFX3-2265H from Creative Biomart Category Protein Source E.coli Species Human

RFX3 Blocking Peptide - CBP2008 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

RFX3 Peptide - BS5893P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Transcription factor RFX3(RFX3) - CSB-YP019612HU CSB-EP019612HU CSB-BP019612HU CSB-MP019612HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RFX3 (transcript variant 2) - TP301137 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RFX3 Recombinant Protein Antigen - NBP1-86301PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RFX3 Peptide, Human - M34GP13206H from Creative Peptides Category Peptide Source Synthetic. Species Human

RFX3 peptide - orb217871 from Biorbyt Category Peptide Species Human, Mouse

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