BRD8

Gene Symbol BRD8
Entrez Gene 10902
Alt Symbol SMAP, SMAP2, p120
Species Human
Gene Type protein-coding
Description bromodomain containing 8
Other Description bromodomain-containing protein 8|skeletal muscle abundant protein 2|thyroid hormone receptor coactivating protein of 120 kDa|trCP120
Swissprots O43178 Q58AB0 Q59GN0 Q15355 Q9H0E9 Q969M9
Accessions EAW62159 EAW62160 EAW62161 EAW62162 Q9H0E9 AB209079 BAD92316 AF016270 AAB87858 AK124191 AK225928 AK289951 BAF82640 AK293621 BAG57080 AK297608 BAG59991 AK297756 BAG60105 AK310380 AK312333 BAG35254 AL136823 CAB66757 AL704983 BC008039 AAH08039 BC008076 AAH08076 BU187982 X87613 CAA60949 X94234 CAA63925 XM_005271855 XP_005271912 XM_005271856 XP_005271913 XM_005271857 XP_005271914 XM_005271859 XP_005271916 XM_005271860 XP_005271917 XM_005271861 XP_005271918 XM_005271865 XP_005271922 XM_006714524 XP_006714587 XM_006714525 XP_006714588 XM_011543109 XP_011541411 XM_011543110 XP_011541412 XM_011543111 XP_011541413 XR_948229 XR_948230 NM_001164326 NP_001157798 NM_001300961 NP_001287890 NM_001300962 NP_001287891 NM_001300966 NP_001287895 NM_006696 NP_006687 NM_139199 NP_631938 NM_183359
Function May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1- like complex that specifically mediates the remo
Subcellular Location Nucleus.
Tissue Specificity Expressed in adipose tissue, brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. {ECO:0000269|PubMed:8611617}.

BRD8 (H-15) - sc-130108 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
BRD8 (H-15): sc-130108. Western blot analysis of BRD8 expression in mouse skeletal muscle tissue extract.

BRD8 (E-20) - sc-162575 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BRD8 antibody - ab17969 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling BRD8 with ab17969 at 1/1000 (1µg/ml). Detection: DAB.

Anti-BRD8 antibody - ab84100 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84100 at 1/100 dilution staining BRD8 in human prostate adenocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

Anti-BRD8 Antibody - LS-C48661 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BRD8 Antibody (aa33-128) - LS-C306566 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BRD8 Antibody (aa25-75) - LS-C287136 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BRD8 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BRD8 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB staining using Immunohistochemistry Accessory Kit.

Anti-BRD8 Antibody (aa1000) - LS-C305899 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of BRD8 antibody LS-X223109.

Anti-BRD8 Antibody (aa225-275) - LS-C287137 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BRD8 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-BRD8 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB staining using Immunohistochemistry Accessory Kit.

Anti-BRD8 Antibody (aa200-250) - LS-C286296 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BRD8 by Immunohistochemistry. Sample: FFPE section of human prostate adenocarcinoma. Antibody: Affinity purified rabbit anti-BRD8 used at a dilution of 1:100. Detection: DAB.

Anti-BRD8 Antibody (aa539-588) IHC-plus™ - LS-B10257 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BRD8 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10257 concentration 10 ug/ml.

Anti-BRD8 Antibody - LS-C332042 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

BRD8 Antibody - NB100-79780 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BRD8 Antibody [NB100-79780] - Detection of Human BRD8 by Western Blot. Samples: Nuclear extract (50 and 15 ug) from HeLa cells. Antibody: Affinity purified rabbit anti-BRD8 antibody NB100-79780 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

BRD8 Antibody - NB100-79781 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BRD8 Antibody - NBP1-82457 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: BRD8 Antibody [NBP1-82457] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & mitochondria.

BRD8 Antibody - NBP2-15613 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BRD8 Antibody [NBP2-15613] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE gel, diluted at 1:1000.

BRD8 Antibody (3G8) - H00010902-M01 from Novus Biologicals

Host Mouse
Clonality Monoclonal
Clone 3G8

BRD8 Polyclonal Antibody - bs-6290R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-BRD8 Polyclonal Antibody, Unconjugated (bs-6290R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-BRD8 antibody produced in rabbit - HPA001841 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BRD8: <B>Cat. No. HPA001841</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis shows strong nuclear positivity in cells of seminiferous ducts.

Anti-BRD8 antibody produced in rabbit - SAB2100223 from Sigma-Aldrich

Prices $347.50, $347.50
Sizes 50 µg, 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BRD8: <B>Cat. No.SAB2100223</B>: BRD8 in 293T cell lysate with BRD8 antibody at 1.0 μg/mL.

BRD8 antibody - middle region (ARP34090_P050) - ARP34090_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BRD8 antibody [C1C2], Internal - GTX115500 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-BRD8 antibody [C1C2], Internal used in Western blot. GTX115500

p120 Catenin (phospho Ser268) antibody [EPR2380] - GTX62142 from GeneTex

Prices $329.00
Sizes 100 μl
Host Rabbit
Clonality Monoclonal
Clone EPR2380
Anti-p120 Catenin (phospho Ser268) antibody [EPR2380] used in ICC/IF. GTX62142

p120 Catenin (phospho Thr310) antibody [EPR2382] - GTX62113 from GeneTex

Host Rabbit
Clonality Monoclonal
Clone EPR2382
Anti-p120 Catenin (phospho Thr310) antibody [EPR2382] used in Western blot. GTX62113

p120 Catenin (phospho Thr916) antibody [EPR2383] - GTX62180 from GeneTex

Host Rabbit
Clonality Monoclonal
Clone EPR2383
Anti-p120 Catenin (phospho Thr916) antibody [EPR2383] used in IHC (Formalin-fixed paraffin-embedded sections). GTX62180
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