CHD5

Gene Symbol	CHD5
Entrez Gene	26038
Alt Symbol	CHD-5
Species	Human
Gene Type	protein-coding
Description	chromodomain helicase DNA binding protein 5
Other Description	ATP-dependent helicase CHD5|chromodomain-helicase-DNA-binding protein 5
Swissprots	Q9UFR9 Q8TDI0 Q7LGH2 O75032 Q5TG89
Accessions	EAW71516 Q8TDI0 AB007913 BAA32289 AF425231 AAL98962 AK091386 BAG52346 AK126012 BAC86391 AK127046 BAC86802 AL110281 CAH56404 AL117491 CAB55959 AL137693 CAH56377 AW005809 BC048142 BC146381 AAI46382 BC148803 AAI48804 NM_015557 NP_056372
Function	Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non- methylated 'Lys-4' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 at 'Lys- 27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway, which in turn, prevents cell proliferation. In spermatogenesis, it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, a crucial step in the condensation of spermatid chromatin and the production of f
Subcellular Location	Nucleus {ECO:0000269|PubMed:21931736, ECO:0000269|PubMed:23948251}. Note=Associates with heterochromatin. {ECO:0000250}.
Tissue Specificity	Preferentially expressed in total brain, fetal brain, and cerebellum. It is also moderately expressed in the adrenal gland and detected in testis. {ECO:0000269|PubMed:12592387, ECO:0000269|PubMed:21931736}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Chromodomain Helicase DNA Binding Protein 5, CHD5, Human, ELISA Kit - E-EL-H0738 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 11.25 Range 18.75-1200pg/mL

Chromodomain Helicase DNA Binding Protein 5, CHD5, Mouse, ELISA Kit - E-EL-M0288 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Chromodomain Helicase DNA Binding Protein 5, CHD5, Rat, ELISA Kit - E-EL-R0205 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Chromodomain Helicase DNA Binding Protein 5, CHD5, Rabbit, ELISA Kit - E-EL-RB0483 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Chromodomain Helicase DNA Binding Protein 5, CHD5, Chicken, ELISA Kit - E-EL-Ch1233 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Chromodomain Helicase DNA Binding Protein 5, CHD5, Porcine, ELISA Kit - E-EL-P0244 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Chromodomain Helicase DNA Binding Protein 5, CHD5, Guinea Pig, ELISA Kit - E-EL-GP0837 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Chromodomain Helicase DNA Binding Protein 5, CHD5, Monkey, ELISA Kit - E-EL-MK2176 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

CHD5, ELISA Kit - MBS2509583 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

CHD5, ELISA Kit - MBS2512502 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 11.25pg/mL Range 18.75-1200pg/mL

CHD5, ELISA Kit - MBS2501771 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

CHD5, ELISA Kit - MBS2503065 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 11.25pg/mL Range 18.75-1200pg/mL

CHD5, ELISA Kit - MBS2512848 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 11.25pg/mL Range 18.75-1200pg/mL

CHD5, ELISA Kit - MBS2513617 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

CHD5, ELISA Kit - MBS2509787 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

CHD5, ELISA Kit - MBS2506235 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

Chromodomain helicase DNA binding protein 5 (CHD5), ELISA Kit - MBS7216408 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7241218 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7245320 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7209516 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7202880 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7250779 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7203447 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7219323 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromodomain-helicase-DNA-binding protein 5 (CHD5), ELISA Kit - MBS7202451 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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