KCNE2

Gene Symbol KCNE2
Entrez Gene 9992
Alt Symbol ATFB4, LQT5, LQT6, MIRP1
Species Human
Gene Type protein-coding
Description potassium channel, voltage gated subfamily E regulatory beta subunit 2
Other Description cardiac voltage-gated potassium channel accessory subunit 2|minK-related peptide 1|minK-related peptide-1|minimum potassium ion channel-related peptide 1|potassium channel subunit beta MiRP1|potassium channel subunit, MiRP1|potassium voltage-gated channel subfamily E member 2|potassium voltage-gated channel, Isk-related family, member 2|voltage-gated K+ channel subunit MIRP1
Swissprots Q9Y6J6 A5H1P3 Q52LJ5 D3DSF8
Accessions ABQ01239 EAX09790 EAX09791 Q9Y6J6 AF071002 AAD28086 AF086086 AF302095 AAG13416 BC093892 AAH93892 BC112087 AAI12088 BG221966 DQ192290 ABB00303 NM_172201 NP_751951
Function Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with KCNQ1/KVLTQ1 and elicit a voltage-independent current. May associate with HCN1 and HCN2 and increase potassium current.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in brain, heart, skeletal muscle, pancreas, placenta, kidney, colon and thymus. A small but significant expression is found in liver, ovary, testis, prostate, small intestine and leukocytes. Very low expression, nearly undetectable, in lung and spleen. {ECO:0000269|PubMed:11034315}.
Top Pathways Gastric acid secretion

MiRP1 (H-4) - sc-374667 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MiRP1 (H-4): sc-374667. Western blot analysis of MiRP1 expression in non-transfected (A) and human MiRP1 transfected (B) whole cell lysates.

MiRP1 (A-17) - sc-31400 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MiRP1 (H-70) - sc-25703 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MiRP1 (C-20) - sc-16350 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-KCNE2 antibody - ab69376 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-KCNE2 antibody (ab69376) at 1 µg/ml + Pancreas (Mouse) Tissue Lysate at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL technique

Anti-KCNE2 antibody - ab169381 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-KCNE2 antibody (ab169381) at 1/500 dilutionLane 1 : KCNE2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-MIRP1 / KCNE2 Antibody (aa79-107, AP) - LS-C215370 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (aa79-107, PE) - LS-C215375 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (aa79-107, Biotin) - LS-C215372 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (aa79-107, APC) - LS-C215371 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (aa79-107, Azide-free, HRP) - LS-C215373 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (aa79-107, FITC) - LS-C215374 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (HRP) - LS-C317592 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (FITC) - LS-C317593 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (aa79-107) - LS-C322379 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (Biotin) - LS-C318919 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody - LS-C317595 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MIRP1 / KCNE2 Antibody (aa79-107) - LS-C159969 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KCNE2 Antibody western blot of A549 cell line lysates (35 ug/lane). The KCNE2 antibody detected the KCNE2 protein (arrow).

Anti-MIRP1 / KCNE2 Antibody (aa33-45) IHC-plus™ - LS-B5136 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-KCNE2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5136 concentration 3.75 ug/ml.

MiRP1 Antibody - NBP1-30637 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MiRP1 Antibody - NBP2-38146 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: MiRP1 Antibody [NBP2-38146] - Staining of human stomach shows strong cytoplasmic positivity in subset of glandular cells.

MiRP1 Antibody - NBP2-38653 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: MiRP1 Antibody [NBP2-38653] - Staining of human stomach shows strong cytoplasmic positivity in subset of glandular cells.

MiRP1 Antibody - H00009992-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

MiRP1 Antibody - H00009992-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

KCNE2 Polyclonal Antibody - bs-9930R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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