KCNE2

Gene Symbol	KCNE2
Entrez Gene	9992
Alt Symbol	ATFB4, LQT5, LQT6, MIRP1
Species	Human
Gene Type	protein-coding
Description	potassium channel, voltage gated subfamily E regulatory beta subunit 2
Other Description	cardiac voltage-gated potassium channel accessory subunit 2|minK-related peptide 1|minK-related peptide-1|minimum potassium ion channel-related peptide 1|potassium channel subunit beta MiRP1|potassium channel subunit, MiRP1|potassium voltage-gated channel subfamily E member 2|potassium voltage-gated channel, Isk-related family, member 2|voltage-gated K+ channel subunit MIRP1
Swissprots	Q9Y6J6 A5H1P3 Q52LJ5 D3DSF8
Accessions	ABQ01239 EAX09790 EAX09791 Q9Y6J6 AF071002 AAD28086 AF086086 AF302095 AAG13416 BC093892 AAH93892 BC112087 AAI12088 BG221966 DQ192290 ABB00303 NM_172201 NP_751951
Function	Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current. May associate with KCNQ1/KVLTQ1 and elicit a voltage-independent current. May associate with HCN1 and HCN2 and increase potassium current.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in brain, heart, skeletal muscle, pancreas, placenta, kidney, colon and thymus. A small but significant expression is found in liver, ovary, testis, prostate, small intestine and leukocytes. Very low expression, nearly undetectable, in lung and spleen. {ECO:0000269|PubMed:11034315}.
Top Pathways	Gastric acid secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KCNE2 full length protein - ab132549 from Abcam Category Protein Source Wheat germ Species Human

Human KCNE2 peptide - ab86641 from Abcam Category Peptide

Human KCNE2 protein fragment - ab160752 from Abcam Category Protein Source Wheat germ Species Human

MIRP1 / KCNE2 Antibody Blocking Peptide - LS-E6502 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MiRP1 Recombinant Protein - H00009992-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human MiRP1 Protein - H00009992-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

KCNE2-Antibody-C-term-Blocking-Peptide - BP19267b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KCNE2 - H00009992-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

KCNE2 - H00009992-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

KCNE2 - H00009992-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

KCNE2 - H00009992-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

KCNE2 fusion protein - Ag12522 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

KCNE2 fusion protein - Ag12336 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human KCNE2, His-tagged - KCNE2-240H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Potassium voltage-gated channel subfamily E member 2(KCNE2) - CSB-YP896548HU CSB-EP896548HU CSB-BP896548HU CSB-MP896548HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KCNE2 - TP311320 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Potassium voltage-gated channel subfamily E member 2 (KCNE2), Recombinant Protein - MBS1395708 from MyBioSource Category Protein Prices $780.00, $780.00, $1,005.00, $1,005.00, $1,085.00, $1,085.00, $1,540.00, $1,540.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MiRP1 Protein - NBP2-38653PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MiRP1 Recombinant Protein Antigen - NBP2-38146PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KCNE2 Peptide, Human - M34GP07941H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more