PRCP

Gene Symbol PRCP
Entrez Gene 5547
Alt Symbol HUMPCP, PCP
Species Human
Gene Type protein-coding
Description prolylcarboxypeptidase (angiotensinase C)
Other Description angiotensinase C|lysosomal Pro-X carboxypeptidase|lysosomal carboxypeptidase C|proline carboxypeptidase|prolylcarboxypeptidase isoform 1 preproprotein
Swissprots B3KRK5 P42785 B2R7B7 A8MU24 B5BU34
Accessions EAW75074 EAW75075 EAW75076 P42785 AB451270 BAG70084 AB451397 BAG70211 AK090847 BAG52238 AK091786 BAG52417 AK302386 BAH13692 AK312919 BAG35764 BC001500 AAH01500 BI827978 BX537480 DB461615 DQ893068 ABM83994 DQ896321 ABM87320 L13977 AAA99891 XM_005274093 XP_005274150 NM_005040 NP_005031 NM_199418 NP_955450
Function Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Subcellular Location Lysosome.
Tissue Specificity Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.
Top Pathways Protein digestion and absorption

Human PRCP full length protein - ab116920 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab116920 at approximately 80.63kDa. Stained with Coomassie Blue.

Human PRCP full length protein - ab159182 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159182 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human PRCP full length protein - ab198658 from Abcam

Category Protein
Source HEK 293 cells
Species Human
10% SDS-Page analysis of ab198658 (1 μg)

PRCP Antibody Blocking Peptide - LS-E2400 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Lysosomal Pro-X Carboxypeptidase/PRCP Protein - H00005547-P02 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Lysosomal Pro-X Carboxypeptidase/PRCP Recombinant Protein - H00005547-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

PRCP-Antibody-N-term-Blocking-peptide - BP13385a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human PRCP, CF - 7164-SE-010 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Met1-His496, with a C-terminal 6-His tag

PRCP / PCP - H00005547-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PRCP / PCP - H00005547-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

PRCP / PCP - H00005547-P02 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

PRCP / PCP - H00005547-P02-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PRCP / PCP - H00005547-P02-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

PRCP fusion protein - Ag8869 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

PRCP fusion protein - Ag9095 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

PrCP, Active Human Recombinant Protein - GWB-PSC500 from Genway Biotech

Category Protein
Prices $600.00
Sizes 10 µg
Species Human
PrCP, Active Human Recombinant Protein

Recombinant Human PRCP - PRCP-31107TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Human PRCP, GST-tagged - PRCP-1936H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human PRCP, His-tagged - PRCP-23H from Creative Biomart

Category Protein
Source Mouse NSO Cells
Species Human

Recombinant Prolylcarboxypeptidase (PRCP) - RPB253Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Prolylcarboxypeptidase (PRCP) - RPB253Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Prolylcarboxypeptidase (PRCP) - RPB253Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

Recombinant Human Lysosomal Pro-X carboxypeptidase(PRCP) - CSB-YP018636HU CSB-EP018636HU CSB-BP018636HU CSB-MP018636HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human PRCP Protein, CF - 7164-SE from R&D Systems

Category Protein
Prices $329.00
Sizes 10 µg
Source Mouse myeloma cell line, NS0-derived Met1-His496, with a C-terminal 6-His tag
Species Human

PRCP / PCP (N-term HIS tag, transcript variant 1) - TP760531 from Acris Antibodies

Category Protein
Prices $199.00
Sizes 50 µg
Source E. coli
Species Human
PRCP / PCP
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