PRCP

Gene Symbol PRCP
Entrez Gene 5547
Alt Symbol HUMPCP, PCP
Species Human
Gene Type protein-coding
Description prolylcarboxypeptidase (angiotensinase C)
Other Description angiotensinase C|lysosomal Pro-X carboxypeptidase|lysosomal carboxypeptidase C|proline carboxypeptidase|prolylcarboxypeptidase isoform 1 preproprotein
Swissprots B3KRK5 P42785 B2R7B7 A8MU24 B5BU34
Accessions EAW75074 EAW75075 EAW75076 P42785 AB451270 BAG70084 AB451397 BAG70211 AK090847 BAG52238 AK091786 BAG52417 AK302386 BAH13692 AK312919 BAG35764 BC001500 AAH01500 BI827978 BX537480 DB461615 DQ893068 ABM83994 DQ896321 ABM87320 L13977 AAA99891 XM_005274093 XP_005274150 NM_005040 NP_005031 NM_199418 NP_955450
Function Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
Subcellular Location Lysosome.
Tissue Specificity Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.
Top Pathways Protein digestion and absorption

Angiotensinase C CRISPR/Cas9 KO Plasmid (h) - sc-404665 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C HDR Plasmid (h) - sc-404665-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C Double Nickase Plasmid (h) - sc-404665-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C Double Nickase Plasmid (h2) - sc-404665-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C CRISPR Activation Plasmid (h) - sc-404665-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C CRISPR Activation Plasmid (h2) - sc-404665-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C Lentiviral Activation Particles (h) - sc-404665-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C Lentiviral Activation Particles (h2) - sc-404665-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Angiotensinase C siRNA (h) - sc-60170 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Angiotensinase C shRNA Plasmid (h) - sc-60170-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Angiotensinase C shRNA (h) Lentiviral Particles - sc-60170-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU052031 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17367 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17367 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04432 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04432

PRCP siRNA (Human) - CRH3724 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human PRCP siRNA - orb264226 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRCP shRNA Plasmid (Human) - CHH3724 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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