Tlr2

Gene Symbol	Tlr2
Entrez Gene	24088
Alt Symbol	Ly105
Species	Mouse
Gene Type	protein-coding
Description	toll-like receptor 2
Other Description	-
Swissprots	Q9QUN7 Q9DBC4 Q3U400
Accessions	EDL15415 Q9QUN7 AF124741 AAD46481 AF165189 AAD49335 AF185284 AAF04277 AF216289 AAF28345 AK005043 BAB23770 AK154504 BAE32635 AY179346 AAO21125 BC014693 AAH14693 BP771904 BY743020 XM_006501460 XP_006501523 NM_011905 NP_036035
Function	Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein.
Tissue Specificity	Detected in a macrophage cell line, smooth muscle, lung, spleen, thymus, brain and adipose tissue.
Top Pathways	Herpes simplex infection, Proteoglycans in cancer, Leishmaniasis, Inflammatory bowel disease (IBD), PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse Tlr2 ORF clone - CDCH091430 from Creative Biomart Species Mouse Accession NM_011905

Mouse Tlr2 ORF clone - CDCH091431 from Creative Biomart Species Mouse Accession NM_011905

Mouse Tlr2 ORF Clone(NM_011905.3) - CDCL178600 from Creative Biomart Species Mouse Accession NM_011905.3

Mouse Tlr2 ORF Clone(NM_011905.3) - CDCR251555 from Creative Biomart Species Mouse Accession NM_011905.3

Mouse Tlr2 ORF Clone(NM_011905.3) - CDCR251556 from Creative Biomart Species Mouse Accession NM_011905.3

Mouse TLR2 ORF clone(NM_011905.3) - CDCL186471 from Creative Biomart Species Mouse Accession NM_011905.3

Mouse TLR2 (CD282) Gene ORF cDNA clone in cloning vector - MG50502-M from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG50502-ACG from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG50502-ACR from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid - MG50502-UT from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, C-HA tag - MG50502-CY from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, N-Flag tag - MG50502-NF from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, C-His tag - MG50502-CH from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, C-Flag tag - MG50502-CF from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, N-HA tag - MG50502-NY from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, N-Myc tag - MG50502-NM from Sino Biological Species Mouse

Mouse CD282 / TLR2 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-tagged - MG50502-M-M from Sino Biological Species Mouse Accession NM_011905.3

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, N-His tag - MG50502-NH from Sino Biological Species Mouse

Mouse TLR2 (CD282) Gene ORF cDNA clone expression plasmid, C-Myc tag - MG50502-CM from Sino Biological Species Mouse

Mouse TLR2 ORF clone(NM_011905.3) - CDCL186471 from Creative biogene Species Mouse

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