Tlr2

Gene Symbol	Tlr2
Entrez Gene	24088
Alt Symbol	Ly105
Species	Mouse
Gene Type	protein-coding
Description	toll-like receptor 2
Other Description	-
Swissprots	Q9QUN7 Q9DBC4 Q3U400
Accessions	EDL15415 Q9QUN7 AF124741 AAD46481 AF165189 AAD49335 AF185284 AAF04277 AF216289 AAF28345 AK005043 BAB23770 AK154504 BAE32635 AY179346 AAO21125 BC014693 AAH14693 BP771904 BY743020 XM_006501460 XP_006501523 NM_011905 NP_036035
Function	Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein.
Tissue Specificity	Detected in a macrophage cell line, smooth muscle, lung, spleen, thymus, brain and adipose tissue.
Top Pathways	Herpes simplex infection, Proteoglycans in cancer, Leishmaniasis, Inflammatory bowel disease (IBD), PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse-TLR2-Antibody-C-term-Blocking-Peptide - BP1502c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

Mouse-TLR2-Antibody-N-term-Blocking-Peptide - BP1502b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

Recombinant Mouse TLR2 Fc Chimera, CF - 1530-TR-050 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Mouse CD282 protein (His Tag) - orb138391 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Baculovirus-Insect Cells Species Mouse

Recombinant Mouse Tlr2, His tagged - Tlr2-7396M from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Mouse

Mouse TLR2 Protein (His Tag) - 50502-M08B-50 from Sino Biological Category Protein Prices $178.00, $178.00 Sizes 50 µg, 100 µg Source Baculovirus-Insect Cells Species Mouse

Recombinant Mouse Toll-like receptor 2(Tlr2) - CSB-YP023601MO CSB-EP023601MO CSB-BP023601MO CSB-MP023601MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse TLR2 Fc Chimera Protein, CF - 1530-TR from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Mouse TLR2 (Gln25-Leu590) Accession # Q9QUN7 DIEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Mouse

TLR2, Peptide - MBS843649 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

Recombinant Mouse TLR2 Protein (His tag) - PKSM040645 from Elabscience Category Protein Source Baculoviru Species Mouse

TLR2 Recombinant Protein (OPCD07491) - OPCD07491 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Mouse TLR2 Protein (His Tag) - 50502-M08B from ABclonal Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Baculovirus-Insect Cells Species Mouse

Tlr2, 25-587aa, Mouse, hIgG-His-tag, Baculovirus - ATGP3597 from ATGen Category Protein Prices $240.00, $960.00 Sizes 10 µg, 50 µg Species Mouse

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