PSMD11

Gene Symbol PSMD11
Entrez Gene 5717
Alt Symbol Rpn6, S9, p44.5
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Other Description 26S proteasome non-ATPase regulatory subunit 11|26S proteasome regulatory subunit 9|26S proteasome regulatory subunit RPN6|26S proteasome regulatory subunit S9|26S proteasome regulatory subunit p44.5
Swissprots A8K3I7 E1P663 Q53FT5 O00231 O00495
Accessions EAW80229 EAW80230 O00231 AB003102 BAA19748 AF001212 AAB58732 AK093602 AK223196 BAD96916 AK290602 BAF83291 AK300342 BAG62087 BC000437 AAH00437 BC004430 AAH04430 BP246240 BQ006240 NM_001270482 NP_001257411 NM_002815 NP_002806
Function Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity. {ECO:0000269|PubMed:22972301}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Tissue Specificity Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate. {ECO:0000269|PubMed:22972301}.
Top Pathways Proteasome, Epstein-Barr virus infection

PSMD11 (D1T1R) Rabbit mAb - 14303 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1T1R
Western blot analysis of extracts from various cell lines using PSMD11 (D1T1R) Rabbit mab.

PSMD11 (H-297) - sc-367988 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PSMD11 (H-297): sc-367988. Western blot analysis of PSMD11 expression in HeLa (A), NIH/3T3 (B) and Hep G2 (C) whole cell lysates and mouse kidney (D) and mouse brain (E) tissue extracts.

PSMD11 (P-20) - sc-79275 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PSMD11 (P-20): sc-79275. Western blot analysis of PSMD11 expression in P19 whole cell lysate.

PSMD11 (O-23) - sc-133933 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PSMD11 (O-23): sc-133933. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.

Anti-PSMD11 antibody [AT1F4] - ab89599 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT1F4
Anti-PSMD11 antibody [AT1F4] (ab89599) at 1/250 dilution + mouse kidney extracts at 60 µgSecondarygoat anti-mouse HRPdeveloped using the ECL technique

Anti-PSMD11 Antibody (aa271-320) IHC-plus™ - LS-B11384 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PSMD11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11384 concentration 20 ug/ml.

Anti-PSMD11 Antibody (C-Terminus) IHC-plus™ - LS-B7777 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PSMD11 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7777 dilution 10 ug/ml.

Anti-PSMD11 Antibody (aa405-423) - LS-C3300 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (aa406-423) - LS-C3301 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (clone AT1F4) - LS-C103489 from LifeSpan Bioscience

Prices $255.00, $315.00
Sizes 50 µl, 100 µl
Host Mouse
Clonality Monoclonal
Clone AT1F4

Anti-PSMD11 Antibody (aa1-422) - LS-C131661 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-PSMD11 Antibody (Arg310) - LS-C192096 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody - LS-C211225 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (FITC) - LS-C211226 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (HRP) - LS-C211227 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (Biotin) - LS-C211229 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (aa175-225) - LS-C289462 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (N-Terminus) - LS-C80000 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.

Anti-PSMD11 Antibody (aa372-422) - LS-C289464 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMD11 Antibody (aa276-325) - LS-C31009 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
PSMD11 antibody LS-C31009 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-PSMD11 Antibody (aa261-310) - LS-C200540 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from RAW264.7cells using PSMD11 antibody.

Anti-PSMD11 Antibody (N-Terminus) - LS-C109654 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMD11 antibody LS-C109654 Western blot of OVCAR-3 cell lysate.

PSMD11 Antibody (1F4) - NBP1-30252 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F4
Western Blot: PSMD11 Antibody (AT1F4) [NBP1-30252] - The extracts of mouse kidney (60ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PSMD11 (1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

PSMD11 Antibody - NBP1-46192 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PSMD11 Antibody [NBP1-46192] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells.  Affinity purified rabbit anti-PSMD11 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  PSMD11 was also immunoprecipitated by rabbit anti-PSMD11 antibody NBP1-46191, which recognizes an upstream epitope.

PSMD11 Antibody - NBP1-46191 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PSMD11 Antibody [NBP1-46191] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells.  Affinity purified rabbit anti-PSMD11 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  PSMD11 was also immunoprecipitated by rabbit anti-PSMD11 antibody NBP1-46192, which recognizes a downstream epitope.
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