PSMD11

Gene Symbol PSMD11
Entrez Gene 5717
Alt Symbol Rpn6, S9, p44.5
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Other Description 26S proteasome non-ATPase regulatory subunit 11|26S proteasome regulatory subunit 9|26S proteasome regulatory subunit RPN6|26S proteasome regulatory subunit S9|26S proteasome regulatory subunit p44.5
Swissprots A8K3I7 E1P663 Q53FT5 O00231 O00495
Accessions EAW80229 EAW80230 O00231 AB003102 BAA19748 AF001212 AAB58732 AK093602 AK223196 BAD96916 AK290602 BAF83291 AK300342 BAG62087 BC000437 AAH00437 BC004430 AAH04430 BP246240 BQ006240 NM_001270482 NP_001257411 NM_002815 NP_002806
Function Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity. {ECO:0000269|PubMed:22972301}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
Tissue Specificity Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate. {ECO:0000269|PubMed:22972301}.
Top Pathways Proteasome, Epstein-Barr virus infection

PSMD11 CRISPR/Cas9 KO Plasmid (h) - sc-410966 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 HDR Plasmid (h) - sc-410966-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 Double Nickase Plasmid (h) - sc-410966-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 Double Nickase Plasmid (h2) - sc-410966-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 CRISPR Activation Plasmid (h) - sc-410966-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 CRISPR Activation Plasmid (h2) - sc-410966-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 Lentiviral Activation Particles (h) - sc-410966-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 Lentiviral Activation Particles (h2) - sc-410966-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 siRNA (h) - sc-76277 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PSMD11 shRNA Plasmid (h) - sc-76277-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PSMD11 shRNA (h) Lentiviral Particles - sc-76277-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU040561 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17616 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17616 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01596 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01596

PSMD11 siRNA (Human) - CRH3862 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PSMD11 (NM_002815.3) - SHH385372 from Creative biogene

Category siRNA
Species Reactivities Human

PSMD11 CRISPR/Cas9 KO Plasmid (h2) - sc-410966-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 HDR Plasmid (h2) - sc-410966-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PSMD11 shRNA Plasmid (Human) - CHH3862 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PSMD11 miRNA 3'UTR clone - MiUTR3H-06811 from Creative biogene

Species Reactivities Human
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