SPDEF

Gene Symbol SPDEF
Entrez Gene 25803
Alt Symbol PDEF, bA375E1.3
Species Human
Gene Type protein-coding
Description SAM pointed domain containing ETS transcription factor
Other Description SAM pointed domain-containing Ets transcription factor|prostate epithelium-specific Ets transcription factor|prostate-derived Ets factor|prostate-specific Ets
Swissprots B4DWH8 O95238 F5H778
Accessions CAC19002 CAC19004 CAC43877 CAI23605 EAX03788 O95238 AB031549 BAA89543 AF071538 AAC95296 AK301543 BAG63040 BC021299 AAH21299 EU446697 ABZ92226 EU832677 ACE87768 EU832757 ACE87089 XM_005248988 XP_005249045 XM_011514457 XP_011512759 NM_001252294 NP_001239223 NM_012391 NP_036523
Function May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT- 3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter. {ECO:0000269|PubMed:10625666}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells. {ECO:0000269|PubMed:10625666}.

PDEF (G-10) - sc-166846 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PDEF (G-10): sc-166846. Western blot analysis of PDEF expression in non-transfected: sc-117752 (A) and human PDEF transfected: sc-177713 (B) 293T whole cell lysates and PC-3 nuclear extract (C).

PDEF (H-250) - sc-67022 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PDEF (H-250): sc-67022. Western blot analysis of PDEF expression in non-transfected: sc-117752 (A) and mouse PDEF transfected: sc-122460 (B) 293T whole cell lysates.

PDEF (C-14) - sc-46443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PDEF (N-14) - sc-46446 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDEF (N-14): sc-46446. Western blot analysis of PDEF expression in DU 145 (A), MCF7 (B), PC-3 (C) and SK-BR-3 (D) nuclear extracts and MDA-MB-231 (E) whole cell lysate.

PDEF (K-14) - sc-46445 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SPDEF antibody - ab197375 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human tonsil cancer tissue, labeling SPDEF with ab197375 at 1/60 dilution.

Anti-SPDEF antibody - ab53881 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SPDEF antibody - ab57042 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57042 SPDEF antibody at 1ug/ml.

Anti-PDEF / SPDEF Antibody (aa182-231) IHC-plus™ - LS-B10250 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PDEF / SPDEF antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10250 concentration 10 ug/ml.

Anti-PDEF / SPDEF Antibody (Internal) - LS-C17400 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PDEF / SPDEF Antibody (aa31-80) - LS-C40289 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SPDEF antibody LS-C40289 Western blot of MCF7 cell lysate.

Anti-PDEF / SPDEF Antibody (aa74-123) - LS-C80011 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PDEF / SPDEF Antibody (C-Terminus) - LS-C135069 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SPDEF antibody LS-C135069 Western blot of Fetal Muscle lysate. Antibody concentration 1 ug/ml.

Anti-PDEF / SPDEF Antibody - LS-C178808 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

SPDEF Antibody - NBP1-74237 from Novus Biologicals

Prices $139.00, $369.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SPDEF Antibody [NBP1-74237] - Human Fetal Muscle Cell Lysate, concentration 1 ug/ml.

SPDEF Antibody (4A5) - H00025803-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A5
Western Blot: SPDEF Antibody (4A5) [H00025803-M01] - Analysis of SPDEF expression in transfected 293T cell line by SPDEF monoclonal antibody (M01), clone 4A5.Lane 1: SPDEF transfected lysate(37.518 KDa).Lane 2: Non-transfected lysate.

SPDEF Antibody - H00025803-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PDEF/SPDEF Polyclonal Antibody - bs-1866R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SPDEF antibody produced in rabbit - AV31841 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: MCF7 (<B>Cat. No. AV31841</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 2.5 μg/mL in cell type MCF7

Anti-SPDEF (AB2) antibody produced in rabbit - AV32534 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HeLa (<B>Cat. No. AV32534</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type HeLa

Anti-SPDEF (AB1) antibody produced in rabbit - AV32533 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: placenta (<B>Cat. No. AV32533</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type placenta

Monoclonal Anti-SPDEF antibody produced in mouse - WH0025803M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4A5
<B>Immunoblotting</B><BR/>Monoclonal Anti-SPDEF, <B>Cat. No. WH0025803M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~38.1 kDa using immunogen protein lysate.

SPDEF antibody - N-terminal region (ARP31841_T100) - ARP31841_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SPDEF antibody - middle region (ARP32533_P050) - ARP32533_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SPDEF antibody - N-terminal region (ARP32534_P050) - ARP32534_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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