SPDEF

Gene Symbol SPDEF
Entrez Gene 25803
Alt Symbol PDEF, bA375E1.3
Species Human
Gene Type protein-coding
Description SAM pointed domain containing ETS transcription factor
Other Description SAM pointed domain-containing Ets transcription factor|prostate epithelium-specific Ets transcription factor|prostate-derived Ets factor|prostate-specific Ets
Swissprots B4DWH8 O95238 F5H778
Accessions CAC19002 CAC19004 CAC43877 CAI23605 EAX03788 O95238 AB031549 BAA89543 AF071538 AAC95296 AK301543 BAG63040 BC021299 AAH21299 EU446697 ABZ92226 EU832677 ACE87768 EU832757 ACE87089 XM_005248988 XP_005249045 XM_011514457 XP_011512759 NM_001252294 NP_001239223 NM_012391 NP_036523
Function May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT- 3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter. {ECO:0000269|PubMed:10625666}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells. {ECO:0000269|PubMed:10625666}.

PDEF CRISPR/Cas9 KO Plasmid (h) - sc-418600 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF HDR Plasmid (h) - sc-418600-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF Double Nickase Plasmid (h) - sc-418600-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF Double Nickase Plasmid (h2) - sc-418600-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF CRISPR Activation Plasmid (h) - sc-418600-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF CRISPR Activation Plasmid (h2) - sc-418600-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF Lentiviral Activation Particles (h) - sc-418600-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF Lentiviral Activation Particles (h2) - sc-418600-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PDEF siRNA (h) - sc-45845 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDEF shRNA Plasmid (h) - sc-45845-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PDEF shRNA (h) Lentiviral Particles - sc-45845-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU043941 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20440 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20440 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05431 from Sigma-Aldrich

Category miRNA

SPDEF siRNA (Human) - CRH8507 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPDEF RNAi - H00025803-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SPDEF - MBS8215024 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SPDEF (NM_012391.2) - SHH416352 from Creative biogene

Category siRNA
Species Reactivities Human

SPDEF shRNA Plasmid (Human) - CHH8507 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SPDEF miRNA 3'UTR clone - MiUTR3H-09783 from Creative biogene

Species Reactivities Human
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