SPDEF

Gene Symbol SPDEF
Entrez Gene 25803
Alt Symbol PDEF, bA375E1.3
Species Human
Gene Type protein-coding
Description SAM pointed domain containing ETS transcription factor
Other Description SAM pointed domain-containing Ets transcription factor|prostate epithelium-specific Ets transcription factor|prostate-derived Ets factor|prostate-specific Ets
Swissprots B4DWH8 O95238 F5H778
Accessions CAC19002 CAC19004 CAC43877 CAI23605 EAX03788 O95238 AB031549 BAA89543 AF071538 AAC95296 AK301543 BAG63040 BC021299 AAH21299 EU446697 ABZ92226 EU832677 ACE87768 EU832757 ACE87089 XM_005248988 XP_005249045 XM_011514457 XP_011512759 NM_001252294 NP_001239223 NM_012391 NP_036523
Function May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT- 3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter. {ECO:0000269|PubMed:10625666}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells. {ECO:0000269|PubMed:10625666}.

SPDEF-Over-expression-Lysate - LY14107a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag SPDEF (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPDEF gene.

SPDEF overexpression lysate - LY415796 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

SPDEF 293 Cell Lysate - 407422 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

SPDEF Overexpression Lysate (Native) - NBL1-16390 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: SPDEF Overexpression Lysate (Adult Normal) [NBL1-16390] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SPDEF.

PDEF (h2): 293T Lysate - sc-177713 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

SPDEF Over-expression Lysate Product - GWB-A28ADB from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human SPDEF Knockdown Stable Cell Line - CSC-DC015018 from Creative biogene

Category Cell Line
Species Human
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